PDB entry 2nww

View 2nww on RCSB PDB site
Description: Crystal structure of GltPh in complex with TBOA
Class: transport protein
Keywords: amino acid transporter, transmembrane transporter, aspartate transporter, binding site, inhibitor binding binding, TRANSPORT PROTEIN
Deposited on 2006-11-16, released 2007-02-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.242
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 425aa long hypothetical proton glutamate symport protein
    Species: Pyrococcus horikoshii [TaxId:53953]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O59010
      • engineered (36)
      • engineered (39)
      • engineered (124)
      • engineered (131)
      • engineered (222)
      • engineered (263)
      • engineered (367)
    Domains in SCOPe 2.07: d2nwwa1
  • Chain 'B':
    Compound: 425aa long hypothetical proton glutamate symport protein
    Species: Pyrococcus horikoshii [TaxId:53953]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O59010
      • engineered (36)
      • engineered (39)
      • engineered (124)
      • engineered (131)
      • engineered (222)
      • engineered (263)
      • engineered (367)
    Domains in SCOPe 2.07: d2nwwb1
  • Chain 'C':
    Compound: 425aa long hypothetical proton glutamate symport protein
    Species: Pyrococcus horikoshii [TaxId:53953]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O59010
      • engineered (36)
      • engineered (39)
      • engineered (124)
      • engineered (131)
      • engineered (222)
      • engineered (263)
      • engineered (367)
    Domains in SCOPe 2.07: d2nwwc1
  • Heterogens: TB1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nwwA (A:)
mglyrkyieypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmp
ivfaslvvgaasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggq
qfqphqapplvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksa
etlldainglaeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvglt
lqillvyfvllkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiys
ftlplgatinmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgaga
imlamvlhsvglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivaktegtlv
pr

    Sequence, based on observed residues (ATOM records): (download) 
    >2nwwA (A:)
ypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmpivfaslvvg
aasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggqqfqphqapp
lvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksaetlldaing
laeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvgltlqillvyfv
llkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiysftlplgati
nmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgagaimlamvlhs
vglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivakte

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nwwB (B:)
mglyrkyieypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmp
ivfaslvvgaasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggq
qfqphqapplvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksa
etlldainglaeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvglt
lqillvyfvllkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiys
ftlplgatinmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgaga
imlamvlhsvglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivaktegtlv
pr

    Sequence, based on observed residues (ATOM records): (download) 
    >2nwwB (B:)
ypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmpivfaslvvg
aasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggqqfqphqapp
lvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksaetlldaing
laeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvgltlqillvyfv
llkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiysftlplgati
nmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgagaimlamvlhs
vglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivakte

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2nwwC (C:)
mglyrkyieypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmp
ivfaslvvgaasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggq
qfqphqapplvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksa
etlldainglaeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvglt
lqillvyfvllkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiys
ftlplgatinmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgaga
imlamvlhsvglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivaktegtlv
pr

    Sequence, based on observed residues (ATOM records): (download) 
    >2nwwC (C:)
ypvlqkiliglilgaivglilghygyahavhtyvkpfgdlfvrllkmlvmpivfaslvvg
aasisparlgrvgvkivvyylltsafavtlgiimarlfnpgagihlavggqqfqphqapp
lvhilldivptnpfgalangqvlptiffaiilgiaitylmnsenekvrksaetlldaing
laeamykivngvmqyapigvfaliayvmaeqgvhvvgelakvtaavyvgltlqillvyfv
llkiygidpisfikhakdamltafvtrsssgtlpvtmrvakemgisegiysftlplgati
nmdgtalyqgvctffianalgshltvgqqltivltavlasigtagvpgagaimlamvlhs
vglpltdpnvaaayamilgidaildmgrtmvnvtgdltgtaivakte