SCOPe 2.04: Structural Classification of Proteins

PDB entry 2nvt

View 2nvt on RCSB PDB site
Description: RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP
Class: transcription,transferase/DNA-RNA hybrid
Keywords: transcription, mRNA, multiprotein complex, molecular machine, DNA, transcription,transferase/DNA-RNA hybrid complex
Deposited on 2006-11-13, released 2006-12-12
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.36 Å
R-factor: 0.232
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: DNA-directed RNA polymerase II largest subunit
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P04050
Domains in SCOPe 2.04: d2nvta1
Chain 'B':
Compound: DNA-directed RNA polymerase II 140 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P08518 (Start-1223)
Domains in SCOPe 2.04: d2nvtb1
Chain 'C':
Compound: DNA-directed RNA polymerase II 45 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P16370
Domains in SCOPe 2.04: d2nvtc1, d2nvtc2
Chain 'E':
Compound: DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20434 (Start-214)
Domains in SCOPe 2.04: d2nvte1, d2nvte2
Chain 'F':
Compound: DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20435 (Start-154)
Domains in SCOPe 2.04: d2nvtf1
Chain 'H':
Compound: DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P20436 (Start-145)
Domains in SCOPe 2.04: d2nvth1
Chain 'I':
Compound: DNA-directed RNA polymerase II subunit 9
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P27999
Domains in SCOPe 2.04: d2nvti1, d2nvti2
Chain 'J':
Compound: DNA-directed RNA polymerases I/II/III subunit 10
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P22139 (0-End)
Domains in SCOPe 2.04: d2nvtj1
Chain 'K':
Compound: DNA-directed RNA polymerase II 13.6 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P38902 (0-End)
Domains in SCOPe 2.04: d2nvtk1
Chain 'L':
Compound: DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide
Species: Saccharomyces cerevisiae [TaxId:4932]
Database cross-references and differences (RAF-indexed):
- Uniprot P40422 (Start-69)
Domains in SCOPe 2.04: d2nvtl1
Chain 'N':
Compound: 5'-d(*gp*tp*ap*cp*tp*tp*g)-3'
Chain 'R':
Compound: 5'-r(*ap*ap*gp*ap*cp*cp*ap*gp*gp*c)-3'
Chain 'T':
Compound: 5'-d(p*cp*ap*ap*gp*tp*ap*cp*tp*tp*ap*cp*gp*cp*cp*tp*gp*gp*tp*cp*tp*t)-3'
Heterogens: ZN, MG, G2P

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>2nvtA (A:)
mvgqqyssaplrtvkevqfglfspeevraisvakirfpetmdetqtrakigglndprlgs
idrnlkcqtcqegmnecpghfghidlakpvfhvgfiakikkvcecvcmhcgkllldehne
lmrqalaikdskkrfaaiwtlcktkmvcetdvpseddptqlvsrggcgntqptirkdglk
lvgswkkdratgdadepelrvlsteeilnifkhisvkdftslgfnevfsrpewmiltclp
vppppvrpsisfnesqrgeddltfkladilkanisletlehngaphhaieeaesllqfhv
atymdndiagqpqalqksgrpvksirarlkgkegrirgnlmgkrvdfsartvisgdpnle
ldqvgvpksiaktltypevvtpynidrltqlvrngpnehpgakyvirdsgdridlryskr
agdiqlqygwkverhimdndpvlfnrqpslhkmsmmahrvkvipystfrlnlsvtspyna
dfdgdemnlhvpqseetraelsqlcavplqivspqsnkpcmgivqdtlcgirkltlrdtf
ieldqvlnmlywvpdwdgviptpaiikpkplwsgkqilsvaipngihlqrfdegttllsp
kdngmliidgqiifgvvekktvgssngglihvvtrekgpqvcaklfgniqkvvnfwllhn
gfstgigdtiadgptmreitetiaeakkkvldvtkeaqanlltakhgmtlresfednvvr
flneardkagrlaevnlkdlnnvkqmvmagskgsfiniaqmsacvgqqsvegkriafgfv
drtlphfskddyspeskgfvensylrgltpqefffhamggreglidtavktaetgyiqrr
lvkaledimvhydnttrnslgnviqfiygedgmdaahiekqsldtiggsdaafekryrvd
llntdhtldpsllesgseilgdlklqvlldeeykqlvkdrkflrevfvdgeanwplpvni
rriiqnaqqtfhidhtkpsdltikdivlgvkdlqenllvlrgkneiiqnaqrdavtlfcc
llrsrlatrrvlqeyrltkqafdwvlsnieaqflrsvvhpgemvgvlaaqsigepatqmt
lntfhfagvaskkvtsgvprlkeilnvaknmktpsltvylepghaadqeqaklirsaieh
ttlksvtiaseiyydpdprstvipedeeiiqlhfslldeeaeqsfdqqspwllrleldra
amndkdltmgqvgerikqtfkndlfviwsedndekliircrvvrpksldaeteaeedhml
kkientmlenitlrgveniervvmmkydrkvpsptgeyvkepewvletdgvnlsevmtvp
gidptriytnsfidimevlgieagraalykevynviasdgsyvnyrhmallvdvmttqgg
ltsvtrhgfnrsntgalmrcsfeetveilfeagasaelddcrgvsenvilgqmapigtga
fdvmideeslvkympeqkiteiedgqdggvtpysnesglvnadldvkdelmfsplvdsgs
ndamaggftayggadygeatspfgaygeaptspgfgvsspgfsptsptysptspayspts
psysptspsysptspsysptspsysptspsysptspsysptspsysptspsysptspsys
ptspsysptspsysptspsysptspsysptspsysptspaysptspsysptspsysptsp
sysptspsysptspnysptspsysptspgyspgspayspkqdeqkhnenensr