PDB entry 2nvb

View 2nvb on RCSB PDB site
Description: Contribution of Pro275 to the Thermostability of the Alcohol Dehydrogenases (ADHs)
Class: oxidoreductase
Keywords: Rossmann fold, Structural Genomics, Israel Structural Proteomics Center, ISPC, OXIDOREDUCTASE
Deposited on 2006-11-12, released 2007-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.217
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NADP-dependent alcohol dehydrogenase
    Species: Thermoanaerobacter brockii [TaxId:29323]
    Gene: ADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14941 (0-351)
      • engineered (274)
    Domains in SCOPe 2.08: d2nvba1, d2nvba2
  • Chain 'B':
    Compound: NADP-dependent alcohol dehydrogenase
    Species: Thermoanaerobacter brockii [TaxId:29323]
    Gene: ADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14941 (0-351)
      • engineered (274)
    Domains in SCOPe 2.08: d2nvbb1, d2nvbb2
  • Chain 'C':
    Compound: NADP-dependent alcohol dehydrogenase
    Species: Thermoanaerobacter brockii [TaxId:29323]
    Gene: ADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14941 (0-351)
      • engineered (274)
    Domains in SCOPe 2.08: d2nvbc1, d2nvbc2
  • Chain 'D':
    Compound: NADP-dependent alcohol dehydrogenase
    Species: Thermoanaerobacter brockii [TaxId:29323]
    Gene: ADH
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14941 (0-351)
      • engineered (274)
    Domains in SCOPe 2.08: d2nvbd1, d2nvbd2
  • Heterogens: ZN, NAP

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nvbA (A:)
mkgfamlsigkvgwiekekpapgpfdaivrplavapctsdihtvfegaigerhnmilghe
avgevvevgsevkdfkpgdrvvvpaitpdwrtsevqrgyhqhsggmlagwkfsnvkdgvf
geffhvndadmnlahlpkeipleaavmipdmmttgfhgaeladielgatvavlgigpvgl
mavagaklrgagriiavgsrpvcvdaakyygatdivnykdgpiesqimnltegkgvdaai
iaggnadimatavkivkpggtianvnyfgegevldvprlewgcgmahktikgglcpggrl
rmerlidlvfykrvdpsklvthvfrgfdniekafmlmkdkpkdlikpvvila

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nvbB (B:)
mkgfamlsigkvgwiekekpapgpfdaivrplavapctsdihtvfegaigerhnmilghe
avgevvevgsevkdfkpgdrvvvpaitpdwrtsevqrgyhqhsggmlagwkfsnvkdgvf
geffhvndadmnlahlpkeipleaavmipdmmttgfhgaeladielgatvavlgigpvgl
mavagaklrgagriiavgsrpvcvdaakyygatdivnykdgpiesqimnltegkgvdaai
iaggnadimatavkivkpggtianvnyfgegevldvprlewgcgmahktikgglcpggrl
rmerlidlvfykrvdpsklvthvfrgfdniekafmlmkdkpkdlikpvvila

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nvbC (C:)
mkgfamlsigkvgwiekekpapgpfdaivrplavapctsdihtvfegaigerhnmilghe
avgevvevgsevkdfkpgdrvvvpaitpdwrtsevqrgyhqhsggmlagwkfsnvkdgvf
geffhvndadmnlahlpkeipleaavmipdmmttgfhgaeladielgatvavlgigpvgl
mavagaklrgagriiavgsrpvcvdaakyygatdivnykdgpiesqimnltegkgvdaai
iaggnadimatavkivkpggtianvnyfgegevldvprlewgcgmahktikgglcpggrl
rmerlidlvfykrvdpsklvthvfrgfdniekafmlmkdkpkdlikpvvila

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nvbD (D:)
mkgfamlsigkvgwiekekpapgpfdaivrplavapctsdihtvfegaigerhnmilghe
avgevvevgsevkdfkpgdrvvvpaitpdwrtsevqrgyhqhsggmlagwkfsnvkdgvf
geffhvndadmnlahlpkeipleaavmipdmmttgfhgaeladielgatvavlgigpvgl
mavagaklrgagriiavgsrpvcvdaakyygatdivnykdgpiesqimnltegkgvdaai
iaggnadimatavkivkpggtianvnyfgegevldvprlewgcgmahktikgglcpggrl
rmerlidlvfykrvdpsklvthvfrgfdniekafmlmkdkpkdlikpvvila