PDB entry 2nu6

View 2nu6 on RCSB PDB site
Description: C123aA Mutant of E. coli Succinyl-CoA Synthetase
Class: ligase
Keywords: citric acid cycle, heterotetramer, ligase, ATP-grasp fold, Rossmann fold
Deposited on 2006-11-08, released 2007-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: 0.196
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Succinyl-CoA ligase [ADP-forming] subunit alpha
    Species: Escherichia coli [TaxId:562]
    Gene: sucD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AGE9 (0-End)
      • engineered (122)
      • modified residue (245)
    Domains in SCOPe 2.08: d2nu6a1, d2nu6a2
  • Chain 'B':
    Compound: succinyl-coa synthetase beta chain
    Species: Escherichia coli [TaxId:562]
    Gene: sucC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2nu6b1, d2nu6b2
  • Chain 'D':
    Compound: Succinyl-CoA ligase [ADP-forming] subunit alpha
    Species: Escherichia coli [TaxId:562]
    Gene: sucD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AGE9 (0-End)
      • engineered (122)
      • modified residue (245)
    Domains in SCOPe 2.08: d2nu6d1, d2nu6d2
  • Chain 'E':
    Compound: succinyl-coa synthetase beta chain
    Species: Escherichia coli [TaxId:562]
    Gene: sucC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2nu6e1, d2nu6e2
  • Heterogens: SO4, COA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nu6A (A:)
silidkntkvicqgftgsqgtfhseqaiaygtkmvggvtpgkggtthlglpvfntvreav
aatgatasviyvpapfckdsileaidagikliititegiptldmltvkvkldeagvrmig
pnapgvitpgeckigiqpghihkpgkvgivsrsgtltyeavkqttdygfgqstcvgiggd
pipgsnfidilemfekdpqteaivmigeiggsaeeeaaayikehvtkpvvgyiagvtapk
gkrmghagaiiaggkgtadekfaaleaagvktvrsladigealktvlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nu6A (A:)
silidkntkvicqgftgsqgtfhseqaiaygtkmvggvtpgkggtthlglpvfntvreav
aatgatasviyvpapfckdsileaidagikliititegiptldmltvkvkldeagvrmig
pnapgvitpgeckigiqpghihkpgkvgivsrsgtltyeavkqttdygfgqstcvgiggd
pipgsnfidilemfekdpqteaivmigeiggsaeeeaaayikehvtkpvvgyiagvtapk
gkrmghagaiiaggkgtadekfaaleaagvktvrsladigealktvl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nu6B (B:)
mnlheyqakqlfaryglpapvgyacttpreaeeaaskigagpwvvkcqvhaggrgkaggv
kvvnskedirafaenwlgkrlvtyqtdangqpvnqilveaatdiakelylgavvdrssrr
vvfmasteggveiekvaeetphlihkvaldpltgpmpyqgrelafklglegklvqqftki
fmglatiflerdlalieinplvitkqgdlicldgklgadgnalfrqpdlremrdqsqedp
reaqaaqwelnyvaldgnigcmvngaglamgtmdivklhggepanfldvgggatkervte
afkiilsddkvkavlvnifggivrcdliadgiigavaevgvnvpvvvrlegnnaelgakk
ladsglniiaakgltdaaqqvvaavegk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2nu6D (D:)
silidkntkvicqgftgsqgtfhseqaiaygtkmvggvtpgkggtthlglpvfntvreav
aatgatasviyvpapfckdsileaidagikliititegiptldmltvkvkldeagvrmig
pnapgvitpgeckigiqpghihkpgkvgivsrsgtltyeavkqttdygfgqstcvgiggd
pipgsnfidilemfekdpqteaivmigeiggsaeeeaaayikehvtkpvvgyiagvtapk
gkrmghagaiiaggkgtadekfaaleaagvktvrsladigealktvlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nu6D (D:)
silidkntkvicqgftgsqgtfhseqaiaygtkmvggvtpgkggtthlglpvfntvreav
aatgatasviyvpapfckdsileaidagikliititegiptldmltvkvkldeagvrmig
pnapgvitpgeckigiqpghihkpgkvgivsrsgtltyeavkqttdygfgqstcvgiggd
pipgsnfidilemfekdpqteaivmigeiggsaeeeaaayikehvtkpvvgyiagvtapk
gkrmghagaiiaggkgtadekfaaleaagvktvrsladigealktvl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2nu6E (E:)
mnlheyqakqlfaryglpapvgyacttpreaeeaaskigagpwvvkcqvhaggrgkaggv
kvvnskedirafaenwlgkrlvtyqtdangqpvnqilveaatdiakelylgavvdrssrr
vvfmasteggveiekvaeetphlihkvaldpltgpmpyqgrelafklglegklvqqftki
fmglatiflerdlalieinplvitkqgdlicldgklgadgnalfrqpdlremrdqsqedp
reaqaaqwelnyvaldgnigcmvngaglamgtmdivklhggepanfldvgggatkervte
afkiilsddkvkavlvnifggivrcdliadgiigavaevgvnvpvvvrlegnnaelgakk
ladsglniiaakgltdaaqqvvaavegk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nu6E (E:)
mnlheyqakqlfaryglpapvgyacttpreaeeaaskigagpwvvkcqvhaggrgkaggv
kvvnskedirafaenwlgkrlvtyqtdangqpvnqilveaatdiakelylgavvdrssrr
vvfmasteggveiekvaeetphlihkvaldpltgpmpyqgrelafklglegklvqqftki
fmglatiflerdlalieinplvitkqgdlicldgklgadgnalfrqpdlremrdqsqedp
reaqaaqwelnyvaldgnigcmvngaglamgtmdivklhggepanfldvgggatkervte
afkiilsddkvkavlvnifggivrcdliadgiigavaevgvnvpvvvrlegnnaelgakk
ladsglniiaakgltdaaqqvvaav