PDB entry 2ntl

View 2ntl on RCSB PDB site
Description: Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus
Class: hydrolase
Keywords: alpha-beta-beta-alpha NTN hydrolase fold
Deposited on 2006-11-07, released 2007-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.208
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IMP cyclohydrolase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Gene: PurO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntla_
  • Chain 'B':
    Compound: IMP cyclohydrolase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Gene: PurO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntlb_
  • Chain 'C':
    Compound: IMP cyclohydrolase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Gene: PurO
    Database cross-references and differences (RAF-indexed):
    • Uniprot O27099 (20-221)
      • cloning artifact (16-19)
    Domains in SCOPe 2.08: d2ntlc2, d2ntlc3
  • Chain 'D':
    Compound: IMP cyclohydrolase
    Species: Methanothermobacter thermautotrophicus [TaxId:145262]
    Gene: PurO
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntld_
  • Heterogens: AMZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ntlA (A:)
mgsshhhhhhssglvprgshmylgrilavgrnsngsfvayrvssrsfpnrttsiqeerva
vvpvegherdvfrnpyiayncirivgdtavvsngshtdtiadkvalgmnlrdaiglslla
mdyekdelntpriaaaingseafigivtadglmvsrvpeetpvyistyeqtepaatefka
gspeeaaefilkggefaafthpvtaaaafndgegwnlatrem

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntlA (A:)
mylgrilavgrnsngsfvayrvssrsfpnrttsiqeervavvpvegherdvfrnpyiayn
cirivgdtavvsngshtdtiadkvalgmnlrdaiglsllamdyekdelntpriaaaings
eafigivtadglmvsrvpeetpvyistyeqtepaatefkagspeeaaefilkggefaaft
hpvtaaaafndgegwnlatrem

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ntlB (B:)
mgsshhhhhhssglvprgshmylgrilavgrnsngsfvayrvssrsfpnrttsiqeerva
vvpvegherdvfrnpyiayncirivgdtavvsngshtdtiadkvalgmnlrdaiglslla
mdyekdelntpriaaaingseafigivtadglmvsrvpeetpvyistyeqtepaatefka
gspeeaaefilkggefaafthpvtaaaafndgegwnlatrem

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntlB (B:)
mylgrilavgrnsngsfvayrvssrsfpnrttsiqeervavvpvegherdvfrnpyiayn
cirivgdtavvsngshtdtiadkvalgmnlrdaiglsllamdyekdelntpriaaaings
eafigivtadglmvsrvpeetpvyistyeqtepaatefkagspeeaaefilkggefaaft
hpvtaaaafndgegwnlatrem

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ntlC (C:)
mgsshhhhhhssglvprgshmylgrilavgrnsngsfvayrvssrsfpnrttsiqeerva
vvpvegherdvfrnpyiayncirivgdtavvsngshtdtiadkvalgmnlrdaiglslla
mdyekdelntpriaaaingseafigivtadglmvsrvpeetpvyistyeqtepaatefka
gspeeaaefilkggefaafthpvtaaaafndgegwnlatrem

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntlC (C:)
rgshmylgrilavgrnsngsfvayrvssrsfpnrttsiqeervavvpvegherdvfrnpy
iayncirivgdtavvsngshtdtiadkvalgmnlrdaiglsllamdyekdelntpriaaa
ingseafigivtadglmvsrvpeetpvyistyeqtepaatefkagspeeaaefilkggef
aafthpvtaaaafndgegwnlatrem

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ntlD (D:)
mgsshhhhhhssglvprgshmylgrilavgrnsngsfvayrvssrsfpnrttsiqeerva
vvpvegherdvfrnpyiayncirivgdtavvsngshtdtiadkvalgmnlrdaiglslla
mdyekdelntpriaaaingseafigivtadglmvsrvpeetpvyistyeqtepaatefka
gspeeaaefilkggefaafthpvtaaaafndgegwnlatrem

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntlD (D:)
mylgrilavgrnsngsfvayrvssrsfpnrttsiqeervavvpvegherdvfrnpyiayn
cirivgdtavvsngshtdtiadkvalgmnlrdaiglsllamdyekdelntpriaaaings
eafigivtadglmvsrvpeetpvyistyeqtepaatefkagspeeaaefilkggefaaft
hpvtaaaafndgegwnlatrem