PDB entry 2nti

View 2nti on RCSB PDB site
Description: Crystal structure of PCNA123 heterotrimer.
Class: DNA binding protein
Keywords: protein-protein interaction, PCNA123 heterotrimer, PCNA12 heterodimer, DNA BINDING PROTEIN
Deposited on 2006-11-07, released 2007-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.214
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase sliding clamp b
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnB, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57766 (0-End)
      • engineered (1)
  • Chain 'B':
    Compound: DNA polymerase sliding clamp c
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnC, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q97Z84 (1-End)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d2ntib1, d2ntib2
  • Chain 'C':
    Compound: DNA polymerase sliding clamp A
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnA, pcnA-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntic1, d2ntic2
  • Chain 'D':
    Compound: DNA polymerase sliding clamp b
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnB, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57766 (0-248)
      • engineered (1)
  • Chain 'E':
    Compound: DNA polymerase sliding clamp c
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnC, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q97Z84 (1-245)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d2ntie1, d2ntie2
  • Chain 'F':
    Compound: DNA polymerase sliding clamp A
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnA, pcnA-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntif1, d2ntif2
  • Chain 'G':
    Compound: DNA polymerase sliding clamp b
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnB, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57766 (0-248)
      • engineered (1)
  • Chain 'H':
    Compound: DNA polymerase sliding clamp c
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnC, pcnA-2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q97Z84 (1-245)
      • initiating methionine (0)
    Domains in SCOPe 2.08: d2ntih1, d2ntih2
  • Chain 'I':
    Compound: DNA polymerase sliding clamp A
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Gene: pcnA, pcnA-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ntii1, d2ntii2
  • Heterogens: BR, K, 7PG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ntiB (B:)
mmkakvidavsfsyilrtvgdflseanfivtkegirvsgidpsrvvfldiflpssyfegf
evsqekeiigfkledvndilkrvlkddtlilssneskltltfdgeftrsfelpliqvest
qppsvnlefpfkaqlltitfadiidelsdlgevlnihskenklyfevigdlstakvelst
dngtlleasgadvsssygmeyvanttkmrrasdsmelyfgsqiplklrfklpqegygdfy
iaprad

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntiB (B:)
mmkakvidavsfsyilrtvgdflseanfivtkegirvsgidpsrvvfldiflpssyfegf
evsqekeiigfkledvndilkrvlkddtlilssneskltltfdgeftrsfelpliqvest
qppsvnlefpfkaqlltitfadiidelsdlgevlnihskenklyfevigdlstakvelst
dngtlleasgadvsssygmeyvanttkmrrasdsmelyfgsqiplklrfklpqegygdfy
iapra

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ntiC (C:)
mkvvyddvrvlkdiiqalarlvdeavlkfkqdsvelvaldrahislisvnlpremfkeyd
vndefkfgfntqylmkilkvakrkeaieiasespdsviiniigstnrefnvrnlevseqe
ipeinlqfdisatissdgfksaisevstvtdnvvveghedrilikaegesevevefskdt
gglqdlefskesknsysaeylddvlsltklsdyvkisfgnqkplqlffnmegggkvtyll
apkv

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ntiE (E:)
mmkakvidavsfsyilrtvgdflseanfivtkegirvsgidpsrvvfldiflpssyfegf
evsqekeiigfkledvndilkrvlkddtlilssneskltltfdgeftrsfelpliqvest
qppsvnlefpfkaqlltitfadiidelsdlgevlnihskenklyfevigdlstakvelst
dngtlleasgadvsssygmeyvanttkmrrasdsmelyfgsqiplklrfklpqegygdfy
iaprad

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntiE (E:)
mmkakvidavsfsyilrtvgdflseanfivtkegirvsgidpsrvvfldiflpssyfegf
evsqekeiigfkledvndilkrvlkddtlilssneskltltfdgeftrsfelpliqvest
qppnlefpfkaqlltitfadiidelsdlgevlnihskenklyfevigdlstakvelstdn
gtlleasgadvsssygmeyvanttkmrrasdsmelyfgsqiplklrfklpqegygdfyia
prad

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ntiF (F:)
mkvvyddvrvlkdiiqalarlvdeavlkfkqdsvelvaldrahislisvnlpremfkeyd
vndefkfgfntqylmkilkvakrkeaieiasespdsviiniigstnrefnvrnlevseqe
ipeinlqfdisatissdgfksaisevstvtdnvvveghedrilikaegesevevefskdt
gglqdlefskesknsysaeylddvlsltklsdyvkisfgnqkplqlffnmegggkvtyll
apkv

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ntiH (H:)
mmkakvidavsfsyilrtvgdflseanfivtkegirvsgidpsrvvfldiflpssyfegf
evsqekeiigfkledvndilkrvlkddtlilssneskltltfdgeftrsfelpliqvest
qppsvnlefpfkaqlltitfadiidelsdlgevlnihskenklyfevigdlstakvelst
dngtlleasgadvsssygmeyvanttkmrrasdsmelyfgsqiplklrfklpqegygdfy
iaprad

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2ntiI (I:)
mkvvyddvrvlkdiiqalarlvdeavlkfkqdsvelvaldrahislisvnlpremfkeyd
vndefkfgfntqylmkilkvakrkeaieiasespdsviiniigstnrefnvrnlevseqe
ipeinlqfdisatissdgfksaisevstvtdnvvveghedrilikaegesevevefskdt
gglqdlefskesknsysaeylddvlsltklsdyvkisfgnqkplqlffnmegggkvtyll
apkv

    Sequence, based on observed residues (ATOM records): (download) 
    >2ntiI (I:)
mkvvyddvrvlkdiiqalarlvdeavlkfkqdsvelvaldrahislisvnlpremfkeyd
vndefkfgfntqylmkilkvakrkeaieiasespdsviiniigstnrefnvrnlevseqe
ipnlqfdisatissdgfksaisevstvtdnvvveghedrilikaegesevevefskdtgg
lqdlefskesknsysaeylddvlsltklsdyvkisfgnqkplqlffnmegggkvtyllap
kv