PDB entry 2nqg
View 2nqg on RCSB PDB site
Description: Calpain 1 proteolytic core inactivated by WR18(S,S), an epoxysuccinyl-type inhibitor.
Class: hydrolase
Keywords: epoxide, epoxysuccinyl, protease, peptidase, proteinase, inactivator, inhibitor, hydrolase
Deposited on
2006-10-31, released
2007-01-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-18, with a file datestamp of
2017-10-13.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Calpain-1 catalytic subunit
Species: Rattus norvegicus [TaxId:10116]
Gene: Capn1, Cls1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2nqga_ - Heterogens: CA, NQG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2nqgA (A:)
mglgrhenaikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikw
krptellsnpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegy
agifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyeal
sggctseafedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitf
knlvrghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereql
rvkmedgefwmsfrdfireftkleicnltpdlehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2nqgA (A:)
naikylgqdyenlrarclqngvlfqddafppvshslgfkelgpnssktygikwkrptell
snpqfivdgatrtdicqgalgdcwllaaiasltlnetilhrvvpygqsfqegyagifhfq
lwqfgewvdvvvddllptkdgklvfvhsaqgnefwsallekayakvngsyealsggctse
afedftggvtewydlqkapsdlyqiilkalergsllgcsinisdirdleaitfknlvrgh
aysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdnsyewnkvdpyereqlrvkmedg
efwmsfrdfireftkleicnlt