PDB entry 2npu

View 2npu on RCSB PDB site
Description: The solution structure of the rapamycin-binding domain of mTOR (FRB)
Class: transferase
Keywords: Four-helix bundle, Transferase
Deposited on 2006-10-30, released 2007-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-02-26, with a file datestamp of 2020-02-21.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.03 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: FKBP12-rapamycin complex-associated protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P42345 (26-125)
      • linker (25)
      • engineered (31)
    Domains in SCOPe 2.08: d2npua1, d2npua2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2npuA (A:)
msyyhhhhhhdydipttenlyfqgamelirvpilwhemwhegleeasrlyfgernvkgmf
evleplhammergpqtlketsfnqaygrdlmeaqewcrkymksgnvkdltqawdlyyhvf
rriskq

    Sequence, based on observed residues (ATOM records): (download) 
    >2npuA (A:)
melirvpilwhemwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqa
ygrdlmeaqewcrkymksgnvkdltqawdlyyhvfrriskq