PDB entry 2nof
View 2nof on RCSB PDB site
Description: Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA
Class: Hydrolase, Lyase/DNA
Keywords: N-glycosylase/DNA lyase, DNA repair, 8-oxoguanine, Hydrolase, Lyase-DNA COMPLEX
Deposited on
2006-10-25, released
2006-11-21
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-10-18, with a file datestamp of
2017-10-13.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: N-glycosylase/DNA lyase
Species: Homo sapiens [TaxId:9606]
Gene: OGG1, MMH, MUTM, OGH1
Database cross-references and differences (RAF-indexed):
- Uniprot O15527 (9-End)
- cloning artifact (6-8)
- engineered (146)
- engineered (312)
Domains in SCOPe 2.07: d2nofa1, d2nofa2, d2nofa3 - Chain 'B':
Compound: 5'-d(*gp*gp*tp*ap*gp*ap*cp*cp*tp*gp*gp*ap*cp*gp*c)-3'
- Chain 'C':
Compound: 5'-d(*gp*cp*gp*tp*c*cp*ap*(g42)p*gp*tp*cp*tp*ap*cp*c)-3'
- Heterogens: CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2nofA (A:)
amadigsefghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladq
vwtltqteeqlhctvyrgdksqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqe
vaqkfqgvrllrqdpieclfsficsscnniaritgmverlcqafgprliqlddvtyhgfp
slqalagpeveahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalci
lpgvgtkvadciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnf
frslwgpyagwafavlfsadlrqsr
Sequence, based on observed residues (ATOM records): (download)
>2nofA (A:)
sefghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrsqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfqgvr
llrqdpieclfsficsscnniaritgmverlcqafgprliqlddvtyhgfpslqalagpe
veahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgtkva
dciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwgpya
gwafavlfsadl
- Chain 'B':
No sequence available.
- Chain 'C':
No sequence available.