PDB entry 2nmm

View 2nmm on RCSB PDB site
Description: Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409
Class: hydrolase
Keywords: NESG Q9H0Y3 human phosphohistidine phosphatase, Structural Genomics, PSI-2, Protein Structure Initiative, Northeast Structural Genomics Consortium, HYDROLASE
Deposited on 2006-10-22, released 2007-01-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14 kDa phosphohistidine phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: PHPT1, PHP14
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NRX4
      • modified residue (73)
      • modified residue (104)
    Domains in SCOPe 2.08: d2nmma1
  • Chain 'B':
    Compound: 14 kDa phosphohistidine phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: PHPT1, PHP14
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NRX4 (10-End)
      • cloning artifact (7-9)
      • modified residue (10)
      • modified residue (73)
      • modified residue (104)
    Domains in SCOPe 2.08: d2nmmb2, d2nmmb3
  • Chain 'C':
    Compound: 14 kDa phosphohistidine phosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: PHPT1, PHP14
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NRX4
      • modified residue (73)
      • modified residue (104)
    Domains in SCOPe 2.08: d2nmmc_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nmmA (A:)
mghhhhhhshmavadlalipdvdidsdgvfkyvlirvhsaprsgapaaeskeivrgykwa
eyhadiydkvsgdmqkqgcdceclgggrishqsqdkkihvygysmaygpaqhaistekik
akypdyevtwandgy

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmmA (A:)
avadlalipdvdidsdgvfkyvlirvhsapeskeivrgykwaeyhadiydkvsgdmqkqg
cdceclgggrishqsqdkkihvygysmaygpaqhaistekikakypdyevtwa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2nmmB (B:)
mghhhhhhshmavadlalipdvdidsdgvfkyvlirvhsaprsgapaaeskeivrgykwa
eyhadiydkvsgdmqkqgcdceclgggrishqsqdkkihvygysmaygpaqhaistekik
akypdyevtwandgy

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmmB (B:)
hshmavadlalipdvdidsdgvfkyvlirvhsaskeivrgykwaeyhadiydkvsgdmqk
qgcdceclgggrishqsqdkkihvygysmaygpaqhaistekikakypdyevtwa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2nmmC (C:)
mghhhhhhshmavadlalipdvdidsdgvfkyvlirvhsaprsgapaaeskeivrgykwa
eyhadiydkvsgdmqkqgcdceclgggrishqsqdkkihvygysmaygpaqhaistekik
akypdyevtwandgy

    Sequence, based on observed residues (ATOM records): (download) 
    >2nmmC (C:)
lalipdvdidsdgvfkyvlirvhskeivrgykwaeyhadiydkvsgdmqkqgcdceclgg
grishqsqdkkihvygysmaygpaqhaistekikakypdyevtwan