PDB entry 2m49

View 2m49 on RCSB PDB site
Description: Structural Insights into Human S100B and Basic Fibroblast Growth Factor (FGF2) Interaction
Class: cytokine/metal binding protein
Keywords: S100B, FGF2, CYTOKINE-METAL BINDING PROTEIN complex
Deposited on 2013-02-03, released 2013-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-12-18, with a file datestamp of 2013-12-13.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: fibroblast growth factor 2
  Species: Homo sapiens [TaxId:9606]
  Gene: FGF2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P09038 (0-125)
    • engineered mutation (50)
    • engineered mutation (68)
  Domains in SCOPe 2.08: d2m49a_
• Chain 'B':
  Compound: Protein S100-B
  Species: Homo sapiens [TaxId:9606]
  Gene: S100B
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04271
  Domains in SCOPe 2.08: d2m49b_
• Chain 'C':
  Compound: fibroblast growth factor 2
  Species: Homo sapiens [TaxId:9606]
  Gene: FGF2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P09038 (0-125)
    • engineered mutation (50)
    • engineered mutation (68)
  Domains in SCOPe 2.08: d2m49c_
• Chain 'D':
  Compound: Protein S100-B
  Species: Homo sapiens [TaxId:9606]
  Gene: S100B
  Database cross-references and differences (RAF-indexed):
  • Uniprot P04271 (0-90)
  Domains in SCOPe 2.08: d2m49d_

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2m49A (A:)
  dpkrlycknggfflrihpdgrvdgvreksdphiklqlqaeergvvsikgvsanrylamke
  dgrllasksvtdecffferlesnnyntyrsrkytswyvalkrtgqyklgsktgpgqkail
  flpmsa
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2m49B (B:)
  selekamvalidvfhqysgregdkhklkkselkelinnelshfleeikeqevvdkvmetl
  dndgdgecdfqefmafvamvttacheffehe
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2m49C (C:)
  dpkrlycknggfflrihpdgrvdgvreksdphiklqlqaeergvvsikgvsanrylamke
  dgrllasksvtdecffferlesnnyntyrsrkytswyvalkrtgqyklgsktgpgqkail
  flpmsa
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2m49D (D:)
  selekamvalidvfhqysgregdkhklkkselkelinnelshfleeikeqevvdkvmetl
  dndgdgecdfqefmafvamvttacheffehe