PDB entry 2ly4

View 2ly4 on RCSB PDB site
Description: HMGB1-facilitated p53 DNA binding occurs via HMG-box/p53 transactivation domain interaction and is regulated by the acidic tail
Class: nuclear protein/antitumour protein
Keywords: HMG, p53, TAD, NUCLEAR PROTEIN-ANTITUMOUR PROTEIN complex
Deposited on 2012-09-12, released 2012-10-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-12-26, with a file datestamp of 2012-12-21.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: High mobility group protein B1
    Species: Homo sapiens [TaxId:9606]
    Gene: HMG1, HMGB1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ly4a_
  • Chain 'B':
    Compound: Cellular tumor antigen p53
    Species: Homo sapiens [TaxId:9606]
    Gene: P53, TP53
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ly4A (A:)
gkgdpkkprgkmssyaffvqtcreehkkkhpdasvnfsefskkcserwktmsakekgkfe
dmakadkaryeremktyippkge

  • Chain 'B':
    No sequence available.