PDB entry 2lwi

View 2lwi on RCSB PDB site
Description: Solution structure of H-RasT35S mutant protein in complex with Kobe2601
Class: signaling protein/inhibitor
Keywords: Ras, GTP-Bound Form, SIGNALING PROTEIN-INHIBITOR complex
Deposited on 2012-08-01, released 2013-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.03 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gtpase hras
    Species: Homo sapiens [TaxId:9606]
    Gene: HRAS, HRAS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01112 (6-171)
      • engineered mutation (40)
    Domains in SCOPe 2.08: d2lwia_
  • Heterogens: GNP, MG, KOB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2lwiA (A:)
gplgsdmteyklvvvgaggvgksaltiqliqnhfvdeydpsiedsyrkqvvidgetclld
ildtagqeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlv
gnkcdlaartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

    Sequence, based on observed residues (ATOM records): (download) 
    >2lwiA (A:)
mteyklvvvgaggvgksaltiqliqnhfvdeydpsiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh