PDB entry 2l7m

View 2l7m on RCSB PDB site
Description: Solution Structure of the Pitx2 Homeodomain R24H mutant
Class: transcription
Keywords: Homeodomain, DNA-binding, Transcription
Deposited on 2010-12-14, released 2011-12-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-12-14, with a file datestamp of 2011-12-09.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: Pituitary homeobox 2
    Species: Homo sapiens [TaxId:9606]
    Gene: PITX2, ARP1, RGS, RIEG, RIEG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99697 (2-61)
      • expression tag (0-1)
      • engineered mutation (25)
      • see remark 999 (62-67)
    Domains in SCOPe 2.06: d2l7mp1, d2l7mp2

PDB Chain Sequences:

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2l7mP (P:)
    gsqrrqrthftsqqlqeleatfqrnhypdmstreeiavwtnltearvrvwfknrrakwrk
    reefivtd