PDB entry 2jlr

View 2jlr on RCSB PDB site
Description: dengue virus 4 ns3 helicase in complex with amppnp
Class: hydrolase
Keywords: ribonucleoprotein, nucleotide-binding, helicase, protease, hydrolase, ATP analog, transferase, viral nucleoprotein, endoplasmic reticulum, cleavage on pair of basic residues, multifunctional enzyme, transcription regulation, nucleotidyltransferase, ns3 helicase structure, virion, ATPase, nucleus, membrane, secreted, ATP-binding, RNA-binding, flaviviruses, glycoprotein, RNA-directed RNA polymerase, RNA replication, serine protease, envelope protein, dengue virus, metal-binding, transmembrane, transcription, phosphoprotein, capsid protein
Deposited on 2008-09-15, released 2008-11-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.20375
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine protease subunit ns3
    Species: DENGUE VIRUS 4 [TaxId:408688]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JLR
      • conflict (82)
      • conflict (124)
      • conflict (153)
      • conflict (213)
      • conflict (358)
    • Uniprot Q2YHF0 (Start-450)
    Domains in SCOPe 2.08: d2jlra1
  • Heterogens: MN, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jlrA (A:)
gsamgepdyevdedifrkkrltimdlhpgagktkrilpsivrealkrrlrtlilaptrvv
aaemeealrglpiryqtpavksdhtgreivdlmchatfttrllsstrvpnynlivmdeah
ftdpcsvaargyistrvemgeaaaifmtatppgstdpfpqsnspiediereiperswntg
fdwitdyqgktvwfvpsikagndianclrksgkrviqlsrktfdteypktkltdwdfvvt
tdisemganfragrvidprrclkpviltdgpervilagpipvtpasaaqrrgrigrnpaq
eddqyvfsgdplrndedhahwteakmlldniytpegiiptlfgperektqaidgefrlkg
eqrktfvelmrrgdlpvwlsykvasagisykdrewcftgernnqileenmeveiwtrege
kkklrpkwldarvyadpmalkdfkefasgrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2jlrA (A:)
edifrkkrltimdlhpgagktkrilpsivrealkrrlrtlilaptrvvaaemeealrglp
iryqtpavksdhtgreivdlmchatfttrllsstrvpnynlivmdeahftdpcsvaargy
istrvemgeaaaifmtatppgstdpfpqsnspiediereiperswntgfdwitdyqgktv
wfvpsikagndianclrksgkrviqlsrktfdteypktkltdwdfvvttdisemganfra
grvidprrclkpviltdgpervilagpipvtpasaaqrrgrigrnpaqeddqyvfsgdpl
rndedhahwteakmlldniytpegiiptlfgperektqaidgefrlkgeqrktfvelmrr
gdlpvwlsykvasagisykdrewcftgernnqileenmeveiwtregekkklrpkwldar
vyadpmalkdfkefasgrk