PDB entry 2jkr

View 2jkr on RCSB PDB site
Description: AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
Class: endocytosis
Keywords: phosphoprotein, phosphorylation, protein transport, adaptor, membrane, transport, coated pit, endocytosis, cell membrane, lipid-binding
Deposited on 2008-08-29, released 2008-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-06-20, with a file datestamp of 2012-06-15.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: 0.202
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ap-2 complex subunit alpha-2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17427 (272-620)
    • PDB 2JKR (621-622)
  • Chain 'B':
    Compound: AP-2 complex subunit beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jkrb_
  • Chain 'E':
    Compound: AP-2 complex subunit beta-1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jkre_
  • Chain 'I':
    Compound: ap-2 complex subunit sigma-1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jkri_
  • Chain 'L':
    Compound: ap-2 complex subunit alpha-2
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17427 (272-620)
    • PDB 2JKR (621-622)
  • Chain 'M':
    Compound: ap-2 complex subunit mu-1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: cd4 peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: cd4 peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: ap-2 complex subunit sigma-1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2jkrs_
  • Chain 'U':
    Compound: ap-2 complex subunit mu-1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2jkrB (B:)
mtdskyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqt
dnlelkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkite
ylceplrkclkdedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvana
vaalseiseshpnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsi
cervtprlshansavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqy
valrninlivqkrpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelke
yatevdvdfvrkavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrk
ypnkyesiiatlcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqv
qltlltaivklflkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakev
vlsekpliseetdlieptlldelichigslasvyhkppnafvegshgihrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2jkrB (B:)
kgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqtdnlelkklvyl
ylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkiteylceplrkclk
dedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvanavaalseisesh
pnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsicervtprlsha
nsavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqyvalrninlivq
krpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelkeyatevdvdfvr
kavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrkypnkyesiiat
lcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqvqltlltaivkl
flkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakevvlsekplisee
tdlieptlldelichigslasvyhkppnafv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2jkrE (E:)
mtdskyfttnkkgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqt
dnlelkklvylylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkite
ylceplrkclkdedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvana
vaalseiseshpnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsi
cervtprlshansavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqy
valrninlivqkrpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelke
yatevdvdfvrkavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrk
ypnkyesiiatlcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqv
qltlltaivklflkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakev
vlsekpliseetdlieptlldelichigslasvyhkppnafvegshgihrk

    Sequence, based on observed residues (ATOM records): (download) 
    >2jkrE (E:)
kgeifelkaelnnekkekrkeavkkviaamtvgkdvsslfpdvvncmqtdnlelkklvyl
ylmnyaksqpdmaimavnsfvkdcedpnpliralavrtmgcirvdkiteylceplrkclk
dedpyvrktaavcvaklhdinaqmvedqgfldslrdliadsnpmvvanavaalseisesh
pnsnlldlnpqninklltalnectewgqifildclsnynpkddreaqsicervtprlsha
nsavvlsavkvlmkflellpkdsdyynmllkklapplvtllsgepevqyvalrninlivq
krpeilkqeikvffvkyndpiyvklekldimirlasqaniaqvlaelkeyatevdvdfvr
kavraigrcaikveqsaercvstlldliqtkvnyvvqeaivvirdifrkypnkyesiiat
lcenldsldepdaraamiwivgeyaeridnadellesflegfhdestqvqltlltaivkl
flkkpsetqelvqqvlslatqdsdnpdlrdrgyiywrllstdpvtakevvlsekplisee
tdlieptlldelichigslasvyhkppnafv

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2jkrI (I:)
mirfiliqnragktrlakwymqfdddekqklieevhavvtvrdakhtnfvefrnfkiiyr
ryaglyfcicvdvndnnlayleaihnfvevlneyfhnvceldlvfnfykvytvvdemfla
geiretsqtkvlkqllmlqsle

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2jkrS (S:)
mirfiliqnragktrlakwymqfdddekqklieevhavvtvrdakhtnfvefrnfkiiyr
ryaglyfcicvdvndnnlayleaihnfvevlneyfhnvceldlvfnfykvytvvdemfla
geiretsqtkvlkqllmlqsle

  • Chain 'U':
    No sequence available.