PDB entry 2jko

View 2jko on RCSB PDB site
Description: focal adhesion kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor
Class: transferase
Keywords: tyrosine-protein kinase, tyrosine- protein kinase, kinase, membrane, transferase, ATP-binding, integrin signaling, nucleotide-binding, focal adhesion, cell migration, kinase inhibitor, cell junction, cell membrane, phosphoprotein
Deposited on 2008-08-28, released 2008-09-09
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.18998
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Gallus gallus [TaxId:9031]
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2jkoa_
  • Heterogens: BIJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2jkoA (A:)
    strdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflq
    ealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayql
    stalayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwma
    pesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncppt
    lyslmtkcwaydpsrrprftelkaqlstileeeklq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jkoA (A:)
    yeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflqealt
    mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlstal
    ayleskrfvhrdiaarnvlvsatdcvklgdfgllpikwmapesinfrrftsasdvwmfgv
    cmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprft
    elkaqlstileeeklq