PDB entry 2jkh

View 2jkh on RCSB PDB site
Description: factor xa - cation inhibitor complex
Class: hydrolase
Keywords: plasma, zymogen, secreted, protease, hydrolase, glycoprotein, gamma-carboxyglutamic acid, blood coagulation, coagulation factor, hydroxylation, serine protease, egf-like domain, cleavage on pair of basic residues
Deposited on 2008-08-28, released 2009-01-13
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: 0.196
AEROSPACI score: 0.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (0-End)
      • engineered mutation (137)
    Domains in SCOPe 2.01: d2jkha_
  • Chain 'L':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2jkhl_
  • Heterogens: BI7, CA, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2jkhA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    k
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jkhA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2jkhL (L:)
    rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jkhL (L:)
    klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr