PDB entry 2jhx

View 2jhx on RCSB PDB site
Description: crystal structure of rhogdi e155h, e157h mutant
Class: inhibitor
Keywords: surface entropy reduction, inhibitor, acetylation, gtpase activation, crystal engineering
Deposited on 2007-02-23, released 2007-05-08
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.195
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHX (0-1)
    • engineered mutation (90)
    • engineered mutation (92)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.05: d2jhxa_
• Chain 'B':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHX (0-1)
    • engineered mutation (90)
    • engineered mutation (92)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.05: d2jhxb_
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhxA (A:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraehyhfltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhxB (B:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraehyhfltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw