PDB entry 2jhv

View 2jhv on RCSB PDB site
Description: crystal structure of rhogdi e154a,e155a mutant
Class: inhibitor
Keywords: surface entropy reduction, inhibitor, gtpase activation, crystal engineering
Deposited on 2007-02-23, released 2007-05-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: 0.212
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhva2, d2jhva3
• Chain 'B':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhvb2, d2jhvb3
• Chain 'C':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhvc2, d2jhvc3
• Chain 'D':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhvd2, d2jhvd3
• Chain 'E':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhve2, d2jhve3
• Chain 'F':
  Compound: rho GDP-dissociation inhibitor 1
  Species: Homo sapiens [TaxId:9606]
  Database cross-references and differences (RAF-indexed):
  • PDB 2JHV (0-1)
    • engineered mutation (89-90)
  • Uniprot P52565 (2-137)
  Domains in SCOPe 2.08: d2jhvf2, d2jhvf3
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvA (A:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvB (B:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvC (C:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvD (D:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'E':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvE (E:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw
  

  
  
• Chain 'F':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2jhvF (F:)
  amvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivs
  gmkyiqhtyrkgvkidktdymvgsygpraaayefltpveeapkgmlargsysiksrftdd
  dktdhlswewnltikkdw