PDB entry 2jex

View 2jex on RCSB PDB site
Description: Transcription activator structure reveals redox control of a replication initiation reaction
Class: transcription
Keywords: nuclear protein, DNA replication, phosphorylation, transcription regulation, viral transcription factor, bovine papillomavirus, replication initiation, early protein, transcription, redox control, e1, e2, oxidation, activator, repressor, DNA-binding
Deposited on 2007-01-24, released 2007-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Regulatory protein E2
    Species: Bovine papillomavirus type 1 [TaxId:10559]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03122
      • engineered mutation (171)
    Domains in SCOPe 2.08: d2jexa_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jexA (A:)
metacerlhvaqetqmqliekssdklqdhilywtavrtentllyaarkkgvtvlghcrvp
hsvvcqerakqaiemqlslqelsktefgdepwslldtswdrymsepkrcfkkgarvveve
fdgnasntnwytvysnlymrtedgwqlakagadgtglyyctmagagriyysafgdeaarf
sttghysvrdqdrvyagvsstssdfrdrp

    Sequence, based on observed residues (ATOM records): (download) 
    >2jexA (A:)
tacerlhvaqetqmqliekssdklqdhilywtavrtentllyaarkkgvtvlghcrvphs
vvcqerakqaiemqlslqelsktefgdepwslldtswdrymsepkrcfkkgarvvevefd
gnasntnwytvysnlymrtedgwqlakagadgtglyyctmagagriyysafgdeaarfst
tghysvrdqdrvyagvs