PDB entry 2jew
View 2jew on RCSB PDB site
Description: Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB
Class: hydrolase
Keywords: carboxypeptidase, carboxypeptidase b, direct metal-binding, metalloprotease, protease, hydrolase, zinc, zymogen, exopeptidase
Deposited on
2007-01-24, released
2007-11-20
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-12-20, with a file datestamp of
2017-12-15.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: carboxypeptidase b
Species: Sus scrofa [TaxId:9823]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d2jewa_ - Heterogens: ZN, 720, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2jewA (A:)
ttghsyekynnwetieawtkqvtsenpdlisrtaigttflgnniyllkvgkpgpnkpaif
mdcgfharewishafcqwfvreavltygyeshmteflnkldfyvlpvlnidgyiytwtkn
rmwrktrstnagttcigtdpnrnfdagwcttgastdpcdetycgsaaeseketkaladfi
rnnlssikayltihsysqmilypysydyklpennaelnnlakaavkelatlygtkytygp
gattiypaaggsddwaydqgikysftfelrdkgrygfilpesqiqatceetmlaikyvtn
yvlghl
Sequence, based on observed residues (ATOM records): (download)
>2jewA (A:)
ghsyekynnwetieawtkqvtsenpdlisrtaigttflgnniyllkvgkpgpnkpaifmd
cgfharewishafcqwfvreavltygyeshmteflnkldfyvlpvlnidgyiytwtknrm
wrktrstnagttcigtdpnrnfdagwcttgastdpcdetycgsaaeseketkaladfirn
nlssikayltihsysqmilypysydyklpennaelnnlakaavkelatlygtkytygpga
ttiypaaggsddwaydqgikysftfelrdkgrygfilpesqiqatceetmlaikyvtnyv
lghl