PDB entry 2jed
View 2jed on RCSB PDB site
Description: the crystal structure of the kinase domain of the protein kinase c theta in complex with nvp-xaa228 at 2.32a resolution.
Class: transferase
Keywords: phosphorylation, nucleotide-binding, serine/threonine-protein kinase, transferase, ATP-binding, polymorphism, metal-binding, zinc, kinase, pkc theta, magnesium, zinc-finger, alternative splicing, phorbol-ester binding
Deposited on
2007-01-16, released
2008-02-05
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: 0.188
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein kinase c theta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q04759
- engineered mutation (20)
- engineered mutation (177)
- PDB 2JED
Domains in SCOPe 2.06: d2jeda_ - Chain 'B':
Compound: protein kinase c theta
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot Q04759 (Start-345)
- engineered mutation (20)
- engineered mutation (177)
- PDB 2JED (346-End)
Domains in SCOPe 2.06: d2jedb1, d2jedb2 - Heterogens: LG8, MPD, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2jedA (A:)
epelnkerpslqiklkiedfelhkmlgkgsfgkvflaefkktnqffaikalkkdvvlmdd
dvectmvekrvlslawehpflthmfctfqtkenlffvmeylnggdlmyhiqschkfdlsr
atfyaaeiilglqflhskgivyrdlkldnilldkdghikiadfgmckenmlgdaktnefc
gtpdyiapeillgqkynhsvdwwsfgvllyemligqspfhgqdeeelfhsirmdnpfypr
wlekeakdllvklfvrepekrlgvrgdirqhplfreinweelerkeidppfrpkvkspfd
csnfdkeflnekprlsfadralinsmdqnmfrnfsfmnpgmerlishhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2jedA (A:)
lkiedfelhkmlgkgsfgkvflaefkktnqffaikalkkdvvlmdddvectmvekrvlsl
awehpflthmfctfqtkenlffvmeylnggdlmyhiqschkfdlsratfyaaeiilglqf
lhskgivyrdlkldnilldkdghikiadfgmckenmlgdaktnefcgtpdyiapeillgq
kynhsvdwwsfgvllyemligqspfhgqdeeelfhsirmdnpfyprwlekeakdllvklf
vrepekrlgvrgdirqhplfreinweelerkeidppfrpkvkspfdcsnfdkeflnekpr
lsfadralinsmdqnmfrnfsfmnpg
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2jedB (B:)
epelnkerpslqiklkiedfelhkmlgkgsfgkvflaefkktnqffaikalkkdvvlmdd
dvectmvekrvlslawehpflthmfctfqtkenlffvmeylnggdlmyhiqschkfdlsr
atfyaaeiilglqflhskgivyrdlkldnilldkdghikiadfgmckenmlgdaktnefc
gtpdyiapeillgqkynhsvdwwsfgvllyemligqspfhgqdeeelfhsirmdnpfypr
wlekeakdllvklfvrepekrlgvrgdirqhplfreinweelerkeidppfrpkvkspfd
csnfdkeflnekprlsfadralinsmdqnmfrnfsfmnpgmerlishhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2jedB (B:)
lkiedfelhkmlgkgsfgkvflaefkktnqffaikalkkdvvlmdddvectmvekrvlsl
awehpflthmfctfqtkenlffvmeylnggdlmyhiqschkfdlsratfyaaeiilglqf
lhskgivyrdlkldnilldkdghikiadfgmckenmlgdaktnefcgtpdyiapeillgq
kynhsvdwwsfgvllyemligqspfhgqdeeelfhsirmdnpfyprwlekeakdllvklf
vrepekrlgvrgdirqhplfreinweelerkeidppfrpkvksprlsfadralinsmdqn
mfrnfsfmnpgmerlishhhhh