PDB entry 2jeb

View 2jeb on RCSB PDB site
Description: structure of a 9-subunit archaeal exosome bound to mn ions
Class: hydrolase
Keywords: nuclease, hydrolase, RNA-binding, exonuclease, phosphorolytic, exoribonuclease, RNA degradation, RNA, rrp4, rrp42, rrp41, exosome, archaeal, RNAse ph
Deposited on 2007-01-16, released 2007-04-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.201
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: exosome complex exonuclease 2
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JEB (0-1)
      • engineered mutation (183)
    • Uniprot Q9UXC0 (2-276)
    Domains in SCOPe 2.07: d2jeba1, d2jeba2, d2jeba3
  • Chain 'B':
    Compound: exosome complex exonuclease 1
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2jebb1, d2jebb2
  • Chain 'I':
    Compound: exosome complex RNA-binding protein 1
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2jebi1, d2jebi2
  • Heterogens: MN, 1PE, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2jebA (A:)
    ghmsstpsnqniipiikkesivslfekgirqdgrkltdyrplsitldyakkadgsalvkl
    gttmvlagtkleidkpyedtpnqgnlivnvellplayetfepgppdenaielarvvdrsl
    rdskaldltklviepgksvwtvwldvyvldyggnvldactlasvaalyntkvykveqhsn
    gisvnknevvgklplnypvvtisvakvdkylvvdpdldeesimdakisfsytpdlkivgi
    qksgkgsmslqdidqaentarstavklleelkkhlgi
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jebA (A:)
    ghmsstpsnqniipiikkesivslfekgirqdgrkltdyrplsitldyakkadgsalvkl
    gttmvlagtkleidkpyedtpnqgnlivnvellplayetfepgppdenaielarvvdrsl
    rdskaldltklviepgksvwtvwldvyvldyggnvldactlasvaalyntkvykveqisv
    nknevvgklplnypvvtisvakvdkylvvdpdldeesimdakisfsytpdlkivgiqksg
    kgsmslqdidqaentarstavklleelkkhlgi
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2jebB (B:)
    ghmremlqverpklilddgkrtdgrkpdelrsikielgvlknadgsaifemgntkaiaav
    ygpkemhprhlslpdravlrvryhmtpfstderknpapsrreielskvirealesavlve
    lfprtaidvfteilqadagsrlvslmaaslaladagipmrdliagvavgkadgviildln
    eteamwgeadmpiammpslnqvtlfqlngsmtpdefrqafdlavkginiiynlerealks
    kyvefkeegv
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jebB (B:)
    rpklilddgkrtdgrkpdelrsikielgvlknadgsaifemgntkaiaavygpkemhprh
    lslpdravlrvryhmtpfstderknpapsrreielskvirealesavlvelfprtaidvf
    teilqadagsrlvslmaaslaladagipmrdliagvavgkadgviildlneteamwgead
    mpiammpslnqvtlfqlngsmtpdefrqafdlavkginiiynlerealkskyv
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >2jebI (I:)
    ghmnmsqsqkivlqprsivvpgellaegefqipwspyilkinskyystvvglfdvkdtqf
    eviplegsfyypkindiviglvedveiygwvvdikapykaylpasnllgrsinvgedlrr
    yldvgdyviarienfdrsidpvlsvkgkdlgrvsngividimpvkvprvigknksmyetl
    tsksgcsifvanngriwatcpsrfseeilieairkieneshikgltdrikqfieeklger
    nassgetktns
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jebI (I:)
    kivlqprsivvpgellaegefqipwspyilkinskyystvvglfdvkdtqfeviplegsf
    yypkindiviglvedveiygwvvdikapykaylpasnllgrsinvgedlrryldvgdyvi
    arienfddpvlsvkgkdlgrvsngividimpvkvprvigknksmyetltskfvanngriw
    ailieairkieneshik