PDB entry 2jea

View 2jea on RCSB PDB site
Description: structure of a 9-subunit archaeal exosome bound to RNA
Class: hydrolase
Keywords: nuclease, hydrolase, RNA-binding, exonuclease, phosphorolytic, exoribonuclease, RNA degradation, RNA, rrp4, rrp42, rrp41, exosome, archaeal, RNAse ph
Deposited on 2007-01-16, released 2007-04-03
The last revision prior to the SCOP 1.75 freeze date was dated 2007-04-03, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.33 Å
R-factor: 0.207
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: exosome complex exonuclease 2
    Species: Sulfolobus solfataricus
    Database cross-references and differences (RAF-indexed):
    • PDB 2JEA (0-1)
      • engineered mutation (183)
      • conflict (9)
    • Uniprot Q9UXC0 (2-276)
    Domains in SCOP 1.75: d2jeaa1, d2jeaa2
  • Chain 'B':
    Compound: exosome complex exonuclease 1
    Species: Sulfolobus solfataricus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2jeab1, d2jeab2
  • Chain 'C':
    Compound: RNA
  • Chain 'I':
    Compound: exosome complex RNA-binding protein 1
    Species: Sulfolobus solfataricus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2jeai1, d2jeai2, d2jeai3
  • Heterogens: 1PE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jeaA (A:)
ghmsstpsnqniipiikkesivslfekgirqdgrkltdyrplsitldyakkadgsalvkl
gttmvlagtkleidkpyedtpnqgnlivnvellplayetfepgppdenaielarvvdrsl
rdskaldltklviepgksvwtvwldvyvldyggnvldactlasvaalyntkvykveqhsn
gisvnknevvgklplnypvvtisvakvdkylvvdpdldeesimdakisfsytpdlkivgi
qksgkgsmslqdidqaentarstavklleelkkhlgi

    Sequence, based on observed residues (ATOM records): (download) 
    >2jeaA (A:)
ghmsstpsnqniipiikkesivslfekgirqdgrkltdyrplsitldyakkadgsalvkl
gttmvlagtkleidkpyedtpnqgnlivnvellplayetfepgppdenaielarvvdrsl
rdskaldltklviepgksvwtvwldvyvldyggnvldactlasvaalyntkvykveqhis
vnknevvgklplnypvvtisvakvdkylvvdpdldeesimdakisfsytpdlkivgiqks
gkgsmslqdidqaentarstavklleelkkhlgi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2jeaB (B:)
ghmremlqverpklilddgkrtdgrkpdelrsikielgvlknadgsaifemgntkaiaav
ygpkemhprhlslpdravlrvryhmtpfstderknpapsrreielskvirealesavlve
lfprtaidvfteilqadagsrlvslmaaslaladagipmrdliagvavgkadgviildln
eteamwgeadmpiammpslnqvtlfqlngsmtpdefrqafdlavkginiiynlerealks
kyvefkeegv

    Sequence, based on observed residues (ATOM records): (download) 
    >2jeaB (B:)
erpklilddgkrtdgrkpdelrsikielgvlknadgsaifemgntkaiaavygpkemhpr
hlslpdravlrvryhmtpfstderknpapsrreielskvirealesavlvelfprtaidv
fteilqadagsrlvslmaaslaladagipmrdliagvavgkadgviildlneteamwgea
dmpiammpslnqvtlfqlngsmtpdefrqafdlavkginiiynlerealkskyv

  • Chain 'C':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >2jeaI (I:)
ghmnmsqsqeivlqprsivvpgellaegefqipwspyilkinskyystvvglfdvkdtqf
eviplegsfyypkindiviglvedveiygwvvdikapykaylpasnllgrsinvgedlrr
yldvgdyviarienfdrsidpvlsvkgkdlgrvsngividimpvkvprvigknksmyetl
tsksgcsifvanngriwatcpsrfseeilieairkieneshikgltdrikqfieeklger
nassgetktns

    Sequence, based on observed residues (ATOM records): (download) 
    >2jeaI (I:)
qeivlqprsivvpgellaegefqipwspyilkinskyystvvglfdvkdtqfeviplegs
fyypkindiviglvedveiygwvvdikapykaylpasnllgrsinvgedlrryldvgdyv
iarienfdrsidpvlsvkgkdlgrvsngividimpvkvprvigknksmyetltsksifva
nngriwafseeilieairkieneshik