PDB entry 2jdv

View 2jdv on RCSB PDB site
Description: structure of pka-pkb chimera complexed with a-443654
Class: transferase
Keywords: camp, kinase, myristate, transferase, lipoprotein, serine/threonine-protein kinase, nucleotide-binding, protein kinase inhibitor, ATP-binding, nuclear protein, phosphorylation
Deposited on 2007-01-12, released 2007-02-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.08 Å
R-factor: 0.21
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-DEPENDENT PROTEIN KINASE
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JDV
      • engineered mutation (104)
      • engineered mutation (123)
      • engineered mutation (173)
      • engineered mutation (181)
    • Uniprot P00517 (Start-350)
    Domains in SCOPe 2.08: d2jdva_
  • Chain 'I':
    Compound: cAMP-dependent protein kinase inhibitor alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: L20, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jdvA (A:)
mgnaaaakkgseqesvkeflakakedflkkwenpaqntahldqferiktlgtgsfgrvml
vkhmetgnhyamkildkqkvvklkqiehtlnekrilqavnfpfltklefsfkdnsnlymv
meyapggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenlmidqqgy
ikvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppff
adqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfat
tdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkefsef

    Sequence, based on observed residues (ATOM records): (download) 
    >2jdvA (A:)
vkeflakakedflkkwenpaqntahldqferiktlgtgsfgrvmlvkhmetgnhyamkil
dkqkvvklkqiehtlnekrilqavnfpfltklefsfkdnsnlymvmeyapggemfshlrr
igrfsepharfyaaqivltfeylhsldliyrdlkpenlmidqqgyikvtdfgfakrvkgr
twtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsgk
vrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveapf
ipkfkgpgdtsnfddyeeeeirvsinekcgkefsef

  • Chain 'I':
    No sequence available.