PDB entry 2jcs

View 2jcs on RCSB PDB site
Description: Active site mutant of dNK from D. melanogaster with dTTP bound
Class: transferase
Keywords: kinase, transferase, ATP-binding, DNA synthesis, nucleotide- binding, deoxyribonucleoside kinase
Deposited on 2007-01-03, released 2007-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XZT6
      • engineered mutation (51)
    Domains in SCOPe 2.08: d2jcsa_
  • Chain 'B':
    Compound: deoxynucleoside kinase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9XZT6
      • engineered mutation (51)
    Domains in SCOPe 2.08: d2jcsb_
  • Heterogens: TTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2jcsA (A:)
    maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltdpvekwrnv
    ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
    ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
    qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jcsA (A:)
    tkyaegtqpftvliegnigsgkttylnhfekykndiclltdpvekwrnvngvnllelmyk
    dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
    leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
    ihqrrpqsckvlvldadl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2jcsB (B:)
    maeaascarkgtkyaegtqpftvliegnigsgkttylnhfekykndiclltdpvekwrnv
    ngvnllelmykdpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrr
    ngsleqgmyntleewykfieesihvqadliiylrtspevayerirqrarseescvplkyl
    qelhelhedwlihqrrpqsckvlvldadlnlenigteyqrsessifdais
    

    Sequence, based on observed residues (ATOM records): (download)
    >2jcsB (B:)
    tkyaegtqpftvliegnigsgkttylnhfekykndiclltdpvekwrnvngvnllelmyk
    dpkkwampfqsyvtltmlqshtaptnkklkimersifsarycfvenmrrngsleqgmynt
    leewykfieesihvqadliiylrtspevayerirqrarseescvplkylqelhelhedwl
    ihqrrpqsckvlvldadl