PDB entry 2jbk

View 2jbk on RCSB PDB site
Description: membrane-bound glutamate carboxypeptidase II (gcpii) in complex with quisqualic acid (quisqualate, alpha-amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid)
Class: hydrolase
Keywords: multifunctional enzyme, neurodegenerative disease, glycoprotein, metal-binding, signal-anchor, hydrolase, naaladase, dipeptidase, polymorphism, zinc, psma, antigen, membrane, protease, peptidase, transmembrane, metal- binding, metalloprotease, prostate cancer, carboxypeptidase,
Deposited on 2006-12-07, released 2006-12-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.99 Å
R-factor: 0.21
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2jbka1, d2jbka2, d2jbka3
  • Heterogens: ZN, CA, CL, NAG, QUS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2jbkA (A:)
kssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkef
gldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsa
fspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagak
gvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgi
aeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvk
mhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfg
tlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlr
vdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfev
ffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggm
vfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteia
skfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyage
sfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >2jbkA (A:)
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvy
vnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfa
pgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhp
igyydaqkllekmggsappdsswrgslkvpynvgpgftfstqkvkmhihstnevtriynv
igtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprrtilf
aswdaeefgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslvhnlt
kelkspdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgraryt
knfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlpfdcrdyavv
lrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdfdksnpivlrm
mndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdieskvdpsk
awgevkrqiyvaaftvqaaaetlseva