PDB entry 2ja3

View 2ja3 on RCSB PDB site
Description: cytoplasmic domain of the human chloride transporter clc-5 in complex with ADP
Class: transport protein
Keywords: domain, membrane, chloride, transport, cbs domain, clc, chloride channel, disease mutation, ionic channel, ion transport, transmembrane, transport protein, chloride transporter, voltage-gated channel
Deposited on 2006-11-21, released 2007-01-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: 0.28
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-End)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3a1, d2ja3a2
  • Chain 'B':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-End)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3b1, d2ja3b2
  • Chain 'C':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-184)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3c1, d2ja3c2
  • Chain 'D':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-End)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3d1, d2ja3d2
  • Chain 'E':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-End)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3e1, d2ja3e2
  • Chain 'F':
    Compound: chloride channel protein 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2JA3 (177-End)
    • Uniprot P51795 (Start-176)
    Domains in SCOPe 2.08: d2ja3f1, d2ja3f2
  • Heterogens: ADP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ja3A (A:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3A (A:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspftvtdltpme
ivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanfneflev

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ja3B (B:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3B (B:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspftvtdltpme
ivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqlfneflevlf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ja3C (C:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3C (C:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspftvtdltpme
ivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqlfneflevlfq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ja3D (D:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3D (D:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspftvtdltpme
ivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdlfneflevl

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ja3E (E:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3E (E:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspftvtdltpme
ivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanfneflev

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ja3F (F:)
meakeefahktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresq
rlvgfvlrrdliisienarkkqdgvvstsiiyftehspplppytpptlklrnildlspft
vtdltpmeivvdifrklglrqclvthngrllgiitkkdvlkhiaqmanqdpdsilfnefl
evlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >2ja3F (F:)
hktlamdvmkprrndplltvltqdsmtvedvetiisettysgfpvvvsresqrlvgfvlr
rdliisienarkgvvstsiiyftehspplppytpptlklrnildlspftvtdltpmeivv
difrklglrqclvthngrllgiitkkdvlkhiaqmilfnefl