PDB entry 2j92

View 2j92 on RCSB PDB site
Description: 3c protease from type a10(61) foot-and-mouth disease virus-crystal packing mutant (k51q)
Class: hydrolase
Keywords: foot-and- mouth disease virus, chymotrypsin-like cysteine protease, hydrolase, thiol protease, RNA replication
Deposited on 2006-11-01, released 2006-12-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.229
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: picornain 3c
    Species: FOOT-AND-MOUTH DISEASE VIRUS (STRAIN A10-61) [TaxId:12112]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03306 (Start-206)
      • conflict (22)
      • conflict (88)
      • engineered mutation (51)
      • engineered mutation (95)
      • engineered mutation (142)
      • engineered mutation (163)
    • PDB 2J92 (207-End)
    Domains in SCOPe 2.08: d2j92a1
  • Chain 'B':
    Compound: picornain 3c
    Species: FOOT-AND-MOUTH DISEASE VIRUS (STRAIN A10-61) [TaxId:12112]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03306 (Start-206)
      • conflict (22)
      • conflict (88)
      • engineered mutation (51)
      • engineered mutation (95)
      • engineered mutation (163)
    • PDB 2J92
    Domains in SCOPe 2.08: d2j92b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2j92A (A:)
esgapptdlqkmvmgntkpvelildgktvaiccatgvfgtaylvprhlfaeqydkimldg
ramtdsdyrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvv
nnadvgrlifsgealtykdivvsmdgdtmpglfaykaatragyaggavlakdgadtfivg
thsaggngvgycscvsrsmlqkmkahveh

    Sequence, based on observed residues (ATOM records): (download) 
    >2j92A (A:)
dlqkmvmgntkpvelildgktvaiccatgvfgtaylvprhlfaeqydkimldgramtdsd
yrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvvnnadvgr
lifsgealtykdivvsmdgdtmpglfaykaatragyaggavlakdgadtfivgthsaggn
gvgycscvsrsmlqkmkahve

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2j92B (B:)
esgapptdlqkmvmgntkpvelildgktvaiccatgvfgtaylvprhlfaeqydkimldg
ramtdsdyrvfefeikvkgqdmlsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvv
nnadvgrlifsgealtykdivvsmdgdtmpglfaykaatragyaggavlakdgadtfivg
thsaggngvgycscvsrsmlqkmkahveh

    Sequence, based on observed residues (ATOM records): (download) 
    >2j92B (B:)
dlqkmvmgntkpvelildgktvaiccatgvfgtaylvprhlfaeqydkimldgramtdsd
yrvfefelsdaalmvlhrgnkvrditkhfrdtarmkkgtpvvgvvnnadvgrlifsgeal
tykdivmpglfaykaatragyaggavlakdgadtfivgthsaggngvgycscvsrsmlqk
mkahv