PDB entry 2j4w

View 2j4w on RCSB PDB site
Description: Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex
Class: immune system
Keywords: immunoglobulin domain, immunoglobulin c region, membrane, transmembrane, hypothetical protein, antibody cross-reactivity, surface active protein, malaria vaccine candidate, apical membrane antigen 1, immune system
Deposited on 2006-09-07, released 2007-01-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'D':
    Compound: apical membrane antigen 1
    Species: PLASMODIUM VIVAX [TaxId:5855]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9TY14
      • engineered mutation (398)
    Domains in SCOPe 2.08: d2j4wd1
  • Chain 'H':
    Compound: fab fragment of monoclonal antibody f8.12.19
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2J4W (223-224)
    Domains in SCOPe 2.08: d2j4wh1, d2j4wh2
  • Chain 'L':
    Compound: fab fragment of monoclonal antibody f8.12.19
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2J4W (0-212)
    Domains in SCOPe 2.08: d2j4wl1, d2j4wl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2j4wD (D:)
ptverstrmgnpwkafmekydierthssgvrvdlgedaevenakyripagrcpvfgkgiv
iensdvsflrpvatgdqklkdggfafpnandhispmtlanlkerykdnvemmklndialc
rthaasfvmagdqnsnyrhpavydekektchmlylsaqenmgprycspdaqnrdavfcfk
pdkdesfenlvylsknvrndwdkkcprknlgnakfglwvdgnceeipyvkeveaedlrec
nrivfgasasdqptqyeeemtdyqkiqqgfrqnnremikgaflpvgafnsdnfkskgrgf
nwanfdsvkrkcyifntkptclindknfiattalshpqevdlefpcsiykdeiereikkq
srnmnlysvdgerivlprifisndkesikcpceperisestcnfyvcncvekraeikeln
qvvikeefrlyyelgeeksnkqmll

    Sequence, based on observed residues (ATOM records): (download) 
    >2j4wD (D:)
ifisndkesikcpceperisestcnfyvcncvek

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2j4wH (H:)
evqlvesggglvkpggslklscaasgfifsdyymywvrqtpekrlewvatisdgnsytyy
vdsvkgrftisrdnaknnlylqmsslksedtaiyycardgptdssgyggfgywgqgtlvt
vseakttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavl
qsdlytlsssvtvpssprpsetvtcnvahpasstkvdkkivprdc

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2j4wL (L:)
esvlsqspailsaspgekvtmtcrarssvsymhwyqqksgsspkpwihatsnlasgvpar
fsgsgsgtsysltisrveaedaatyycqqwsshpptfgsgtkleikradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec