PDB entry 2j34

View 2j34 on RCSB PDB site
Description: crystal structure of a human factor xa inhibitor complex
Class: hydrolase
Keywords: gamma- carboxyglutamic acid, serine protease, egf-like domain, blood coagulation, polymorphism, glycoprotein, hydroxylation, gamma-carboxyglutamic acid,calcium, zymogen, complex, protease, hydrolase
Deposited on 2006-08-18, released 2006-09-27
The last revision prior to the SCOP 1.75 freeze date was dated 2006-10-11, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: 0.181
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: activated factor xa heavy chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2j34a1
  • Chain 'B':
    Compound: factor x light chain
    Species: HOMO SAPIENS
    Domains in SCOP 1.75: d2j34b1
  • Heterogens: CA, GS6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2j34A (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
kshapevitssplk

    Sequence, based on observed residues (ATOM records): (download) 
    >2j34A (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2j34B (B:)
eemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgkckdgl
geytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladngkaci
ptgpypcgkqtler

    Sequence, based on observed residues (ATOM records): (download) 
    >2j34B (B:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle