PDB entry 2j2u

View 2j2u on RCSB PDB site
Description: crystal structure of a human factor xa inhibitor complex
Class: hydrolase
Keywords: gamma- carboxyglutamic acid, serine protease, egf-like domain, blood coagulation, polymorphism, glycoprotein, hydroxylation, gamma-carboxyglutamic acid, calcium, zymogen, complex, protease, hydrolase
Deposited on 2006-08-17, released 2006-09-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.196
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: coagulation factor x heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2j2ua_
  • Chain 'B':
    Compound: coagulation factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Domains in SCOPe 2.07: d2j2ub_
  • Heterogens: GSQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2j2uA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    kshapevitssplk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j2uA (A:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtqkt
    givsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacqgd
    sggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2j2uB (B:)
    eemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgkckdgl
    geytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladngkaci
    ptgpypcgkqtler
    

    Sequence, based on observed residues (ATOM records): (download)
    >2j2uB (B:)
    rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtl