PDB entry 2j0q

View 2j0q on RCSB PDB site
Description: the crystal structure of the exon junction complex at 3.2 a resolution
Class: hydrolase
Keywords: hydrolase, mRNA processing, mRNA splicing, mRNA transport, nuclear protein, dead-box helicase, RNA-binding
Deposited on 2006-08-04, released 2006-08-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.235
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent RNA helicase ddx48
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qa1, d2j0qa2
  • Chain 'B':
    Compound: ATP-dependent RNA helicase ddx48
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qb1, d2j0qb2
  • Chain 'C':
    Compound: Protein mago nashi homolog
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qc1
  • Chain 'D':
    Compound: RNA-binding protein 8A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qd1
  • Chain 'E':
    Compound: 5'-r(*up*up*up*up*up*up*up*up*up*up*up*up*up*up*u)-3'
  • Chain 'F':
    Compound: Protein mago nashi homolog
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qf1
  • Chain 'G':
    Compound: RNA-binding protein 8A
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2j0qg1
  • Chain 'H':
    Compound: 5'-r(*up*up*up*up*up*up*up*up*up*up*up*up*up*up*u)-3'
  • Chain 'I':
    Compound: Protein CASC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: Protein CASC3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2j0qA (A:)
attatmatsgsarkrllkeedmtkvefetseevdvtptfdtmglredllrgiyaygfekp
saiqqraikqiikgrdviaqsqsgtgktatfsisvlqcldiqvretqalilaptrelavq
iqkgllalgdymnvqchaciggtnvgedirkldygqhvvagtpgrvfdmirrrslrtrai
kmlvldeademlnkgfkeqiydvyrylppatqvvlisatlpheilemtnkfmtdpirilv
krdeltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmrean
ftvssmhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrely
ihrigrsgrygrkgvainfvknddirilrdieqyystqidempmnvadli

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qA (A:)
dmtkvefetseevdvtptfdtmglredllrgiyaygfekpsaiqqraikqiikgrdviaq
sqsgtgktatfsisvlqcldiqvretqalilaptrelavqiqkgllalgdymnvqchaci
ggtnvgedirkldygqhvvagtpgrvfdmirrrslrtraikmlvldeademlnkgfkeqi
ydvyrylppatqvvlisatlpheilemtnkfmtdpirilvkrdeltlegikqffvavere
ewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvssmhgdmpqkeresimk
efrsgasrvlistdvwargldvpqvsliinydlpnnrelyihrigrsgrygrkgvainfv
knddirilrdieqyystqidempmnvadli

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2j0qB (B:)
attatmatsgsarkrllkeedmtkvefetseevdvtptfdtmglredllrgiyaygfekp
saiqqraikqiikgrdviaqsqsgtgktatfsisvlqcldiqvretqalilaptrelavq
iqkgllalgdymnvqchaciggtnvgedirkldygqhvvagtpgrvfdmirrrslrtrai
kmlvldeademlnkgfkeqiydvyrylppatqvvlisatlpheilemtnkfmtdpirilv
krdeltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmrean
ftvssmhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrely
ihrigrsgrygrkgvainfvknddirilrdieqyystqidempmnvadli

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qB (B:)
dmtkvefetseevdvtptfdtmglredllrgiyaygfekpsaiqqraikqiikgrdviaq
sqsgtgktatfsisvlqcldiqvretqalilaptrelavqiqkgllalgdymnvqchaci
ggtnvgedirkldygqhvvagtpgrvfdmirrrslrtraikmlvldeademlnkgfkeqi
ydvyrylppatqvvlisatlpheilemtnkfmtdpirilvkrdeltlegikqffvavere
ewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvssmhgdmpqkeresimk
efrsgasrvlistdvwargldvpqvsliinydlpnnrelyihrigrsgrygrkgvainfv
knddirilrdieqyystqidempmnvadli

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2j0qC (C:)
mesdfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeel
kriiddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglr
vfyylvqdlkclvfsliglhfkikpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qC (C:)
dfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeelkri
iddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglrvfy
ylvqdlkclvfsliglhfkikpi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2j0qD (D:)
pqrsvegwilfvtgvheeateedihdkfaeygeiknihlnldrrtgylkgytlveyetyk
eaqaameglngqdlmgqpisvdwcfvrgppkgkrrggrrrsrspdrrrr

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qD (D:)
pqrsvegwilfvtgvheeateedihdkfaeygeiknihlnldrrtgylkgytlveyetyk
eaqaameglngqdlmgqpisvdwcfvrgp

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2j0qF (F:)
mesdfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeel
kriiddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglr
vfyylvqdlkclvfsliglhfkikpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qF (F:)
dfylryyvghkgkfgheflefefrpdgklryannsnykndvmirkeayvhksvmeelkri
iddseitkeddalwpppdrvgrqeleivigdehisfttskigslidvnqskdpeglrvfy
ylvqdlkclvfsliglhfkikpi

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2j0qG (G:)
pqrsvegwilfvtgvheeateedihdkfaeygeiknihlnldrrtgylkgytlveyetyk
eaqaameglngqdlmgqpisvdwcfvrgppkgkrrggrrrsrspdrrrr

    Sequence, based on observed residues (ATOM records): (download) 
    >2j0qG (G:)
pqrsvegwilfvtgvheeateedihdkfaeygeiknihlnldrrtgylkgytlveyetyk
eaqaameglngqdlmgqpisvdwcfvrgp

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'T':
    No sequence available.