PDB entry 2izr

View 2izr on RCSB PDB site
Description: structure of casein kinase gamma 3 in complex with inhibitor
Class: transferase
Keywords: serine/threonine-protein kinase, kinase, transferase, ATP-binding, phosphorylation, nucleotide-binding, alternative splicing, wnt signaling pathway, serine/threonine kinase
Deposited on 2006-07-26, released 2006-08-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.132
AEROSPACI score: 0.8 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: casein kinase I isoform gamma-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IZR
      • conflict (154)
    • Uniprot Q9Y6M4
    Domains in SCOPe 2.06: d2izra_
  • Heterogens: BRK, MG, CL, PGO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2izrA (A:)
smgvlmvgpnfrvgkkigcgnfgelrlgknlytneyvaiklepmksrapqlhleyrfykq
lgsgdgipqvyyfgpcgkynamvlellgpsledlfdlcdrtfslktvlmiaiqlisrmey
vhsknliyrdvkpenfligrpgnktqqvihiidfalakeyidpetkkhipyrehksltgt
arymsinthlgkeqsrrddlealghmfmyflrgslpwqglkadtlkeryqkigdtkratp
ievlcenfpematylryvrrldffekpdydylrklftdlfdrkgymfdyeydwigkqlpt
pvgavqqdpalssnreahqhrdkmqqsknq

    Sequence, based on observed residues (ATOM records): (download) 
    >2izrA (A:)
vlmvgpnfrvgkkigcnfgelrlgknlytneyvaiklepmksrapqlhleyrfykqlgsg
dgipqvyyfgpcgkynamvlellgpsledlfdlcdrtfslktvlmiaiqlisrmeyvhsk
nliyrdvkpenfligrpgnktqqvihiidfalakeyidpetkkhipyrehksltgtarym
sinthlgkeqsrrddlealghmfmyflrgslpwqglkadtlkeryqkigdtkratpievl
cenfpematylryvrrldffekpdydylrklftdlfdrkgymfdyeydwigkqlptpv