PDB entry 2iy0

View 2iy0 on RCSB PDB site
Description: senp1 (mutant) sumo1 rangap
Class: hydrolase/hydrolase activator
Keywords: hydrolase-hydrolase activator complex, hydrolase-activator complex, protease, hydrolase, ubiquitin, thiol protease, leucine- rich repeat, ubl conjugation pathway, protein protein complex, gtpase activation, hydrolase-activator complex ubl conjugation, nuclear protein, phosphorylation
Deposited on 2006-07-11, released 2006-08-07
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.77 Å
R-factor: 0.23
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sentrin-specific protease 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9P0U3 (175-225)
      • engineered mutation (184)
    • PDB 2IY0 (174-174)
    Domains in SCOPe 2.04: d2iy0a1
  • Chain 'B':
    Compound: Small ubiquitin-related modifier 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2iy0b_
  • Chain 'C':
    Compound: ran gtpase-activating protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2iy0c1
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2iy0A (A:)
efpeiteemekeiknvfrngnqdevlseafrltitrkdiqtlnhlnwlndeiinfymnml
merskekglpsvhafntffftklktagyqavkrwtkkvdvfsvdillvpihlgvhwclav
vdfrkknityydsmgginneacrillqylkqesidkkrkefdtngwqlfskksqeipqqm
ngsdagmfackyadcitkdrpinftqqhmpyfrkrmvweilhrkll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2iy0B (B:)
eyiklkvigqdsseihfkvkmtthlkklkesycqrqgvpmnslrflfegqriadnhtpke
lgmeeedvievyqeqtgghstv

    Sequence, based on observed residues (ATOM records): (download) 
    >2iy0B (B:)
iklkvigqdsseihfkvkmtthlkklkesycqrqgvpmnslrflfegqriadnhtpkelg
meeedvievyqeqtgg

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2iy0C (C:)
advstflafpspekllrlgpkssvliaqqtdtsdpekvvsaflkvssvfkdeatvrmavq
davdalmqkafnsssfnsntfltrllvhmgllksedkvkaianlygplmalnhmvqqdyf
pkalaplllafvtkpnsalescsfarhsllqtlykv