PDB entry 2ixv

View 2ixv on RCSB PDB site
Description: Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant)
Class: hydrolase
Keywords: antimicrobial, muein hydrolase, bacteriolytic enzyme, pneumococcal cell wall degradation, lysozyme, hydrolase, glycosidase, multimodular
Deposited on 2006-07-11, released 2007-07-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lysozyme
    Species: STREPTOCOCCUS PHAGE CP-1 [TaxId:10747]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15057 (Start-338)
      • engineered mutation (93)
    Domains in SCOPe 2.08: d2ixva1, d2ixva2
  • Heterogens: FMT, ALA, DGN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ixvA (A:)
    mvkkndlfvdvsshngyditgileqmgttntiikisesttylnpclsaqveqsnpigfyh
    farfggdvaeaereaqffldnvpmqvkylvldyqddpsgdaqantnaclrfmqmiadagy
    kpiyysykpfthdnvdyqqilaqfpnslwiagyglndgtanfeyfpsmdgirwwqyssnp
    fdknivllddeeddkpktagtwkqdskgwwfrrnngsfpynkwekiggvwyyfdskgycl
    tsewlkdnekwyylkdngamatgwvlvgsewyymddsgamvtgwvkyknnwyymtnergn
    mvsnefiksgkgwyfmntngeladnpsftkepdglitva
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ixvA (A:)
    vkkndlfvdvsshngyditgileqmgttntiikisesttylnpclsaqveqsnpigfyhf
    arfggdvaeaereaqffldnvpmqvkylvldyqddpsgdaqantnaclrfmqmiadagyk
    piyysykpfthdnvdyqqilaqfpnslwiagyglndgtanfeyfpsmdgirwwqyssnpf
    dknivllddeeddkpktagtwkqdskgwwfrrnngsfpynkwekiggvwyyfdskgyclt
    sewlkdnekwyylkdngamatgwvlvgsewyymddsgamvtgwvkyknnwyymtnergnm
    vsnefiksgkgwyfmntngeladnpsftkepdglitva