PDB entry 2ixp

View 2ixp on RCSB PDB site
Description: CRYSTAL STRUCTURE OF THE PP2A PHOSPHATASE ACTIVATOR Ypa1 PTPA1 in complex with model substrate
Class: isomerase/isomerase inhibitor
Keywords: pp2a phosphatase activator prolyl isomerase ptpa, prolyl containing peptide substrate analog, nuclear protein, isomerase-isomerase inhibitor complex
Deposited on 2006-07-09, released 2006-07-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2016-12-28, with a file datestamp of 2016-12-22.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein phosphatase 2a activator 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP
    Domains in SCOPe 2.07: d2ixpa1
  • Chain 'B':
    Compound: serine/threonine-protein phosphatase 2a activator 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP
    Domains in SCOPe 2.07: d2ixpb_
  • Chain 'C':
    Compound: serine/threonine-protein phosphatase 2a activator 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP
    Domains in SCOPe 2.07: d2ixpc_
  • Chain 'D':
    Compound: serine/threonine-protein phosphatase 2a activator 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP
    Domains in SCOPe 2.07: d2ixpd_
  • Chain 'F':
    Compound: sin-ala-ala-pro-lys-nit
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP (0-5)
  • Chain 'G':
    Compound: sin-ala-ala-pro-lys-nit
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP (0-5)
  • Chain 'H':
    Compound: sin-ala-ala-pro-lys-nit
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP (0-5)
  • Chain 'I':
    Compound: sin-ala-ala-pro-lys-nit
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IXP (0-5)
  • Heterogens: SO4, CL

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ixpA (A:)
    msldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphat
    assiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpse
    yhevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnky
    ytimrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvr
    eykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfp
    vvqhfwfgtgffpwvnihhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ixpA (A:)
    sldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphata
    ssiamvnglmgvldklahlidetpplgnlacrewhhklderlpqwlqemlpseyhevvpe
    lqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnkyytimrrl
    iltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvreykdtnf
    ycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfpvvqhfwf
    gtgffpwvni
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ixpB (B:)
    msldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphat
    assiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpse
    yhevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnky
    ytimrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvr
    eykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfp
    vvqhfwfgtgffpwvnihhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ixpB (B:)
    sldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphata
    ssiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpsey
    hevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnkyy
    timrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvre
    ykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfpv
    vqhfwfgtgffpwvni
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2ixpC (C:)
    msldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphat
    assiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpse
    yhevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnky
    ytimrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvr
    eykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfp
    vvqhfwfgtgffpwvnihhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ixpC (C:)
    sldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphata
    ssiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpsey
    hevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnkyy
    timrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvre
    ykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfpv
    vqhfwfgtgffpwvni
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2ixpD (D:)
    msldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphat
    assiamvnglmgvldklahlidetpplpgprrygnlacrewhhklderlpqwlqemlpse
    yhevvpelqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnky
    ytimrrliltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvr
    eykdtnfycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfp
    vvqhfwfgtgffpwvnihhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ixpD (D:)
    sldrvdwphatfstpvkrifdtqttldfqsslaihrikyhlhkyttlishcsdpdphata
    ssiamvnglmgvldklahlidetpplgnlacrewhhklderlpqwlqemlpseyhevvpe
    lqyylgnsfgsstrldygtghelsfmatvaaldmlgmfphmrgadvfllfnkyytimrrl
    iltytlepagshgvwglddhfhlvyilgssqwqlldaqaplqpreildkslvreykdtnf
    ycqginfinevkmgpfeehspilydiavtvprwskvckgllkmysvevlkkfpvvqhfwf
    gtgffpwvni
    

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.