PDB entry 2ixf

View 2ixf on RCSB PDB site
Description: Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant)
Class: hydrolase
Keywords: hydrolase, membrane, transport, abc protein transport, nucleotide-binding
Deposited on 2006-07-08, released 2006-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antigen peptide transporter 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36370 (1-End)
      • engineered mutation (181)
      • engineered mutation (214)
    Domains in SCOPe 2.08: d2ixfa_
  • Chain 'B':
    Compound: antigen peptide transporter 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36370 (1-End)
      • engineered mutation (181)
      • engineered mutation (214)
    Domains in SCOPe 2.08: d2ixfb_
  • Chain 'C':
    Compound: antigen peptide transporter 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36370
      • engineered mutation (181)
      • engineered mutation (214)
    Domains in SCOPe 2.08: d2ixfc_
  • Chain 'D':
    Compound: antigen peptide transporter 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P36370
      • engineered mutation (181)
      • engineered mutation (214)
    Domains in SCOPe 2.08: d2ixfd_
  • Heterogens: ATP, MG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ixfA (A:)
msplsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkst
vaallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrt
ptmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllil
dqatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgth
lqlmerggcyrsmvealaapsdaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ixfA (A:)
splsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkstv
aallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrtp
tmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllild
qatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgthl
qlmerggcyrsmvea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ixfB (B:)
msplsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkst
vaallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrt
ptmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllil
dqatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgth
lqlmerggcyrsmvealaapsdaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ixfB (B:)
splsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkstv
aallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrtp
tmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllild
qatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgthl
qlmerggcyrsmvea

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ixfC (C:)
msplsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkst
vaallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrt
ptmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllil
dqatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgth
lqlmerggcyrsmvealaapsdaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ixfC (C:)
gslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkstvaall
qnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrtptmee
itavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllildqats
aldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgthlqlme
rggcyrsmveal

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ixfD (D:)
msplsgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkst
vaallqnlyqptggkvlldgeplvqydhhylhtqvaavgqepllfgrsfreniaygltrt
ptmeeitavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllil
dqatsaldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgth
lqlmerggcyrsmvealaapsdaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ixfD (D:)
sgslaplnmkglvkfqdvsfaypnhpnvqvlqgltftlypgkvtalvgpngsgkstvaal
lqnlyqptggkvlldgeplvqydhhylhtqvaavgqllfgrsfreniaygltrtptmeei
tavamesgahdfisgfpqgydtevgetgnqlsggqrqavalaralirkprllildqatsa
ldagnqlrvqrllyespewasrtvllithqlslaerahhilflkegsvceqgthlqlmer
ggcyrsmvea