PDB entry 2iwx

View 2iwx on RCSB PDB site
Description: analogues of radicicol bound to the ATP-binding site of hsp90.
Class: chaperone
Keywords: inhibitor, chaperone, heat shock, ATP-binding, multigene family, chaperone-complex, nucleotide- binding
Deposited on 2006-07-05, released 2006-11-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.2
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2iwxa_
  • Heterogens: M1S, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2iwxA (A:)
    masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
    dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
    gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
    qleyleekrikevikrhsefvaypiqlvvtkeve