PDB entry 2iwu

View 2iwu on RCSB PDB site
Description: analogues of radicicol bound to the ATP-binding site of hsp90
Class: chaperone
Keywords: inhibitor, chaperone, heat shock, ATP-binding, multigene family, nucleotide-binding
Deposited on 2006-07-04, released 2006-11-30
The last revision prior to the SCOP 1.73 freeze date was dated 2006-11-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.232
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2iwua1
  • Heterogens: NP5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2iwuA (A:)
    masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
    dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
    gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
    qleyleekrikevikrhsefvaypiqlvvtkeve