PDB entry 2iwt

View 2iwt on RCSB PDB site
Description: Thioredoxin h2 (HvTrxh2) in a mixed disulfide complex with the target protein BASI
Class: oxidoreductase
Keywords: protease inhibitor, disulfide reductase, basi, amy2, redox, thioredoxin, oxidoreductase, substrate recognition, disulfide intermediate, alpha-amylase inhibitor, serine protease inhibitor
Deposited on 2006-07-04, released 2006-11-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-12, with a file datestamp of 2017-07-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thioredoxin h isoform 2
    Species: Hordeum vulgare [TaxId:4513]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IWT
      • engineered mutation (51)
    • Uniprot Q7XZK2
    Domains in SCOPe 2.08: d2iwta_
  • Chain 'B':
    Compound: Alpha-amylase/subtilisin inhibitor
    Species: Hordeum vulgare [TaxId:4513]
    Database cross-references and differences (RAF-indexed):
    • PDB 2IWT
      • engineered mutation (151)
    • Uniprot P07596 (7-188)
    Domains in SCOPe 2.08: d2iwtb_
  • Heterogens: FLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2iwtA (A:)
gshmaasataaavaaevisvhsleqwtmqieeantakklvvidftaswcgpsrimapvfa
dlakkfpnavflkvdvdelkpiaeqfsveamptflfmkegdvkdrvvgaikeeltakvgl
haaaq

    Sequence, based on observed residues (ATOM records): (download) 
    >2iwtA (A:)
evisvhsleqwtmqieeantakklvvidftaswcgpsrimapvfadlakkfpnavflkvd
vdelkpiaeqfsveamptflfmkegdvkdrvvgaikeeltakvglhaaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2iwtB (B:)
mhhhhhhaadpppvhdtdghelradanyyvlsanrahgggltmapghgrhcplfvsqdpn
gqhdgfpvritpygvapsdkiirlstdvrisfrayttclqstewhidselaagrrhvitg
pvkdpspsgrenafriekysgaevheyklmssgdwcqdlgvfrdlkggawflgatepyhv
vvfkkappa

    Sequence, based on observed residues (ATOM records): (download) 
    >2iwtB (B:)
aadpppvhdtdghelradanyyvlsanrahgggltmapghgrhcplfvsqdpngqhdgfp
vritpygvapsdkiirlstdvrisfrayttclqstewhidselaagrrhvitgpvkdpsp
sgrenafriekysgaevheyklmssgdwcqdlgvfrdlkggawflgatepyhvvvfkkap
pa