PDB entry 2iws

View 2iws on RCSB PDB site
Description: Radicicol analogues bound to the ATP site of HSP90
Class: chaperone
Keywords: inhibitor, chaperone, heat shock, ATP-binding, multigene family, nucleotide-binding
Deposited on 2006-07-04, released 2006-11-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent molecular chaperone hsp82
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2iwsa_
  • Heterogens: NP4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2iwsA (A:)
masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
dlfiritpkpeqkvleirdsgigmtkaelinnlgtiaksgtkafmealsagadvsmigqf
gvgfyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkdd
qleyleekrikevikrhsefvaypiqlvvtkeve

    Sequence, based on observed residues (ATOM records): (download) 
    >2iwsA (A:)
masetfefqaeitqlmsliintvysnkeiflrelisnasdaldkirykslsdpkqletep
dlfiritpkpeqkvleirdsgigmtkaelinnlgtigtkafmealsagadvsmigqfgvg
fyslflvadrvqvisksnddeqyiwesnaggsftvtldevnerigrgtilrlflkddqle
yleekrikevikrhsefvaypiqlvvtkeve