PDB entry 2itg

View 2itg on RCSB PDB site
Description: catalytic domain of hiv-1 integrase: ordered active site in the f185h construct
Class: DNA integration
Keywords: DNA integration, aids, polyprotein, hydrolase, endonuclease, polynucleotidyl transferase, DNA binding (viral)
Deposited on 1996-09-13, released 1997-03-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.2
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: human immunodeficiency virus-1 integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • engineered (135)
    Domains in SCOPe 2.08: d2itga_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2itgA (A:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqa
ehlktavqmavfihnhkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >2itgA (A:)
hgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpv
ktvhtdngsnftsttvkaacwwagikqefgipynpqsqgviesmnkelkkiigqvrdqae
hlktavqmavfihnhkrkggiggysagerivdiiatdiqt