PDB entry 2it0

View 2it0 on RCSB PDB site
Description: Crystal structure of a two-domain IdeR-DNA complex crystal form II
Class: transcription/DNA
Keywords: DNA-binding protein, TRANSCRIPTION/DNA COMPLEX
Deposited on 2006-10-18, released 2007-02-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.229
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: iron-dependent repressor ider
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: IdeR,dtxR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A672 (Start-139)
      • expression tag (140-146)
    Domains in SCOPe 2.08: d2it0a1, d2it0a2, d2it0a3
  • Chain 'B':
    Compound: iron-dependent repressor ider
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: IdeR,dtxR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A672 (Start-139)
      • expression tag (140-146)
    Domains in SCOPe 2.08: d2it0b1, d2it0b2, d2it0b3
  • Chain 'C':
    Compound: iron-dependent repressor ider
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: IdeR,dtxR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2it0c1, d2it0c2
  • Chain 'D':
    Compound: iron-dependent repressor ider
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: IdeR,dtxR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2it0d1, d2it0d2
  • Chain 'E':
    Compound: mbtA/mbtB operator strand 1
  • Chain 'F':
    Compound: mbtA/mbtB operator strand 2
  • Heterogens: NI, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2it0A (A:)
    mnelvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdr
    hleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvl
    nnpttspfgnpipglvelgvasenlyfqggghhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2it0A (A:)
    elvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdrhl
    eltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnn
    pttspfgnpipglvelgvasenlyf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2it0B (B:)
    mnelvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdr
    hleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvl
    nnpttspfgnpipglvelgvasenlyfqggghhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2it0B (B:)
    elvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdrhl
    eltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnn
    pttspfgnpipglvelgvasenlyf
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2it0C (C:)
    mnelvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdr
    hleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvl
    nnpttspfgnpipglvelgvasenlyfqggghhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2it0C (C:)
    elvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdrhl
    eltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnn
    pttspfgnpipglvelg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2it0D (D:)
    mnelvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdr
    hleltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvl
    nnpttspfgnpipglvelgvasenlyfqggghhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2it0D (D:)
    elvdttemylrtiydleeegvtplrariaerldqsgptvsqtvsrmerdgllrvagdrhl
    eltekgralaiavmrkhrlaerllvdviglpweevhaeacrwehvmsedverrlvkvlnn
    pttspfgnpipglvelg
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.