PDB entry 2isc

View 2isc on RCSB PDB site
Description: Crystal structure of Purine Nucleoside Phosphorylase from Trichomonas vaginalis with DADMe-Imm-A
Class: transferase
Keywords: purine nucleoside phosphorylase, Transferase
Deposited on 2006-10-17, released 2007-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2isca1, d2isca2
  • Chain 'B':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2iscb1, d2iscb2
  • Chain 'C':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2iscc1, d2iscc2
  • Chain 'D':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2iscd1, d2iscd2
  • Chain 'E':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2isce_
  • Chain 'F':
    Compound: purine nucleoside phosphorylase
    Species: Trichomonas vaginalis [TaxId:5722]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2iscf1, d2iscf2
  • Heterogens: PO4, 223, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2iscA (A:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscA (A:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhqnsfqnmmkialeaaiklh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2iscB (B:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscB (B:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2iscC (C:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscC (C:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhrqnsfqnmmkialeaaiklhhhh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2iscD (D:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscD (D:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhh

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2iscE (E:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscE (E:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhherqnsfqnmmkialeaaikl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2iscF (F:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhheettaeerqnsfqnmmkialeaaiklhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2iscF (F:)
atphnsaqvgdfaetvlmcgdplrakliaetylenpklvnnvrgiqgytgtykgkpisvm
ghgmglpsiciyaeelystykvktiirvgtcgaidmdihtrdiviftsagtnskinrirf
mdhdypatasfdvvcalvdaakelnipakvgkgfstdlfynpqtelaqlmnkfhflavem
esaglfpiadlygaragcictvsdhilhhaeerqnsfqnmmkialeaaiklhh