PDB entry 2ioa

View 2ioa on RCSB PDB site
Description: E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP and phosphinate inhibitor
Class: ligase, hydrolase
Keywords: Bifunctional glutathionylspermidine synthetase/amidase, LIGASE, HYDROLASE
Deposited on 2006-10-10, released 2006-12-12
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.173
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional glutathionylspermidine synthetase/amidase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2ioaa1, d2ioaa2, d2ioaa3
  • Chain 'B':
    Compound: Bifunctional glutathionylspermidine synthetase/amidase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d2ioab1, d2ioab2, d2ioab3
  • Heterogens: MG, GGA, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ioaA (A:)
    mskgttsqdapfgtllgyapggvaiyssdyssldpqeyeddavfrsyiddeymghkwqcv
    efarrflflnygvvftdvgmaweifslrflrevvndnilplqafpngsprapvagalliw
    dkggefkdtghvaiitqlhgnkvriaeqnvihsplpqgqqwtrelemvvengcytlkdtf
    ddttilgwmiqtedteyslpqpeiagellkisgarlenkgqfdgkwldekdplqnayvqa
    ngqvinqdpyhyytitesaeqelikatnelhlmylhatdkvlkddnllalfdipkilwpr
    lrlswqrrrhhmitgrmdfcmderglkvyeynadsaschteaglilerwaeqgykgngfn
    paeglinelagawkhsrarpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelg
    wdaagqlidgegrlvncvwktwawetafdqirevsdrefaavpirtghpqnevrlidvll
    rpevlvfeplwtvipgnkailpilwslfphhrylldtdftvndelvktgyavkpiagrcg
    snidlvshheevldktsgkfaeqkniyqqlwclpkvdgkyiqvctftvggnyggtclrgd
    eslvikkesdieplivvkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ioaA (A:)
    apfgtllgyapggvaiyssdyvfrsyiddeymghkwqcvefarrflflnygvvftdvgma
    weifslrflrevvndnilplqafpngsprapvagalliwdkggefkdtghvaiitqlhgn
    kvriaeqnvihsplpqgqqwtrelemvvengcytlkdtfddttilgwmiqtedteyslpq
    peiagellkisgarlenkgqfdgkwldekdplqnayvqangqvinqdpyhyytitesaeq
    elikatnelhlmylhatdkvlkddnllalfdipkilwprlrlswqrrrhhmitgrmdfcm
    derglkvyeynadsaschteaglilerwaeqgykgngfnpaeglinelagawkhsrarpf
    vhimqdkdieenyhaqfmeqalhqagfetrilrgldelgwqlidgegrlvncvwktwawe
    tafdqirevfaavpirtghpqnevrlidvllrpevlvfeplwtvipgnkailpilwslfp
    hhrylldtdftvndelvktgyavkpiagrcgsnidlvshheevldktsgkfaeqkniyqq
    lwclpkvdgkyiqvctftvggnyggtclrgdeslvikkesdieplivvk
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2ioaB (B:)
    mskgttsqdapfgtllgyapggvaiyssdyssldpqeyeddavfrsyiddeymghkwqcv
    efarrflflnygvvftdvgmaweifslrflrevvndnilplqafpngsprapvagalliw
    dkggefkdtghvaiitqlhgnkvriaeqnvihsplpqgqqwtrelemvvengcytlkdtf
    ddttilgwmiqtedteyslpqpeiagellkisgarlenkgqfdgkwldekdplqnayvqa
    ngqvinqdpyhyytitesaeqelikatnelhlmylhatdkvlkddnllalfdipkilwpr
    lrlswqrrrhhmitgrmdfcmderglkvyeynadsaschteaglilerwaeqgykgngfn
    paeglinelagawkhsrarpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelg
    wdaagqlidgegrlvncvwktwawetafdqirevsdrefaavpirtghpqnevrlidvll
    rpevlvfeplwtvipgnkailpilwslfphhrylldtdftvndelvktgyavkpiagrcg
    snidlvshheevldktsgkfaeqkniyqqlwclpkvdgkyiqvctftvggnyggtclrgd
    eslvikkesdieplivvkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ioaB (B:)
    fgtllgyapggvaiyssdysvfrsyiddeymghkwqcvefarrflflnygvvftdvgmaw
    eifslrflrevvndnilplqafpngsprapvagalliwdkggefkdtghvaiitqlhgnk
    vriaeqnvihsplpqgqqwtrelemvvengcytlkdtfddttilgwmiqtedteyslpqp
    eiagellkisgarlenkgqfdgkwldekdplqnayvqangqvinqdpyhyytitesaeqe
    likatnelhlmylhatdkvlkddnllalfdipkilwprlrlswqrrrhhmitgrmdfcmd
    erglkvyeynadsaschteaglilerwaeqgykgngfnpaeglinelagawkhsrarpfv
    himqdkdieenyhaqfmeqalhqagfetrilrgldelgwgqlidgegrlvncvwktwawe
    tafdqirevfaavpirtghpqnevrlidvllrpevlvfeplwtvipgnkailpilwslfp
    hhrylldtdftvndelvktgyavkpiagrcgsnidlvshheevldktsgkfaeqkniyqq
    lwclpkvdgkyiqvctftvggnyggtclrgdeslvikkesdieplivvk