PDB entry 2ioa

View 2ioa on RCSB PDB site
Description: E. coli Bifunctional glutathionylspermidine synthetase/amidase Incomplex with Mg2+ and ADP and phosphinate inhibitor
Class: ligase, hydrolase
Keywords: Bifunctional glutathionylspermidine synthetase/amidase, LIGASE, HYDROLASE
Deposited on 2006-10-10, released 2006-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.173
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional glutathionylspermidine synthetase/amidase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ioaa1, d2ioaa2, d2ioaa3
  • Chain 'B':
    Compound: Bifunctional glutathionylspermidine synthetase/amidase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ioab1, d2ioab2, d2ioab3
  • Heterogens: MG, GGA, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ioaA (A:)
mskgttsqdapfgtllgyapggvaiyssdyssldpqeyeddavfrsyiddeymghkwqcv
efarrflflnygvvftdvgmaweifslrflrevvndnilplqafpngsprapvagalliw
dkggefkdtghvaiitqlhgnkvriaeqnvihsplpqgqqwtrelemvvengcytlkdtf
ddttilgwmiqtedteyslpqpeiagellkisgarlenkgqfdgkwldekdplqnayvqa
ngqvinqdpyhyytitesaeqelikatnelhlmylhatdkvlkddnllalfdipkilwpr
lrlswqrrrhhmitgrmdfcmderglkvyeynadsaschteaglilerwaeqgykgngfn
paeglinelagawkhsrarpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelg
wdaagqlidgegrlvncvwktwawetafdqirevsdrefaavpirtghpqnevrlidvll
rpevlvfeplwtvipgnkailpilwslfphhrylldtdftvndelvktgyavkpiagrcg
snidlvshheevldktsgkfaeqkniyqqlwclpkvdgkyiqvctftvggnyggtclrgd
eslvikkesdieplivvkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ioaA (A:)
apfgtllgyapggvaiyssdyvfrsyiddeymghkwqcvefarrflflnygvvftdvgma
weifslrflrevvndnilplqafpngsprapvagalliwdkggefkdtghvaiitqlhgn
kvriaeqnvihsplpqgqqwtrelemvvengcytlkdtfddttilgwmiqtedteyslpq
peiagellkisgarlenkgqfdgkwldekdplqnayvqangqvinqdpyhyytitesaeq
elikatnelhlmylhatdkvlkddnllalfdipkilwprlrlswqrrrhhmitgrmdfcm
derglkvyeynadsaschteaglilerwaeqgykgngfnpaeglinelagawkhsrarpf
vhimqdkdieenyhaqfmeqalhqagfetrilrgldelgwqlidgegrlvncvwktwawe
tafdqirevfaavpirtghpqnevrlidvllrpevlvfeplwtvipgnkailpilwslfp
hhrylldtdftvndelvktgyavkpiagrcgsnidlvshheevldktsgkfaeqkniyqq
lwclpkvdgkyiqvctftvggnyggtclrgdeslvikkesdieplivvk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ioaB (B:)
mskgttsqdapfgtllgyapggvaiyssdyssldpqeyeddavfrsyiddeymghkwqcv
efarrflflnygvvftdvgmaweifslrflrevvndnilplqafpngsprapvagalliw
dkggefkdtghvaiitqlhgnkvriaeqnvihsplpqgqqwtrelemvvengcytlkdtf
ddttilgwmiqtedteyslpqpeiagellkisgarlenkgqfdgkwldekdplqnayvqa
ngqvinqdpyhyytitesaeqelikatnelhlmylhatdkvlkddnllalfdipkilwpr
lrlswqrrrhhmitgrmdfcmderglkvyeynadsaschteaglilerwaeqgykgngfn
paeglinelagawkhsrarpfvhimqdkdieenyhaqfmeqalhqagfetrilrgldelg
wdaagqlidgegrlvncvwktwawetafdqirevsdrefaavpirtghpqnevrlidvll
rpevlvfeplwtvipgnkailpilwslfphhrylldtdftvndelvktgyavkpiagrcg
snidlvshheevldktsgkfaeqkniyqqlwclpkvdgkyiqvctftvggnyggtclrgd
eslvikkesdieplivvkk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ioaB (B:)
fgtllgyapggvaiyssdysvfrsyiddeymghkwqcvefarrflflnygvvftdvgmaw
eifslrflrevvndnilplqafpngsprapvagalliwdkggefkdtghvaiitqlhgnk
vriaeqnvihsplpqgqqwtrelemvvengcytlkdtfddttilgwmiqtedteyslpqp
eiagellkisgarlenkgqfdgkwldekdplqnayvqangqvinqdpyhyytitesaeqe
likatnelhlmylhatdkvlkddnllalfdipkilwprlrlswqrrrhhmitgrmdfcmd
erglkvyeynadsaschteaglilerwaeqgykgngfnpaeglinelagawkhsrarpfv
himqdkdieenyhaqfmeqalhqagfetrilrgldelgwgqlidgegrlvncvwktwawe
tafdqirevfaavpirtghpqnevrlidvllrpevlvfeplwtvipgnkailpilwslfp
hhrylldtdftvndelvktgyavkpiagrcgsnidlvshheevldktsgkfaeqkniyqq
lwclpkvdgkyiqvctftvggnyggtclrgdeslvikkesdieplivvk