PDB entry 2ii6

View 2ii6 on RCSB PDB site
Description: Crystal structure of Pasteurella multocida sialyltransferase D141N mutant in open conformation with CMP bound
Class: transferase
Keywords: mutant D141N, sialyltransferase, streak seeding, CMP, two Rossmann domains, TRANSFERASE
Deposited on 2006-09-27, released 2007-08-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.203
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-2,3/2,6-sialyltransferase/sialidase
    Species: Pasteurella multocida [TaxId:747]
    Gene: Pm0188
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15KI8 (1-387)
      • initiating methionine (0)
      • engineered (116)
      • cloning artifact (388-392)
    Domains in SCOPe 2.08: d2ii6a1, d2ii6a2
  • Heterogens: C5P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ii6A (A:)
mktitlyldpaslpalnqlmdftqnnedkthprifglsrfkipdniitqyqnihfvelkd
nrptealftildqypgnielnihlniahsvqlirpilayrfkhldrvsiqqlnlydngsm
eyvdlekeenkdisaeikqaekqlshylltgkikfdnptiaryvwqsafpvkyhflstdy
fekaeflqplkeylaenyqkmdwtayqqltpeqqafyltlvgfndevkqslevqqakfif
tgtttwegntdvreyyaqqqlnllnhftqaegdlfigdhykiyfkghprggeindyilnn
aknitnipanisfevlmmtgllpdkvggvasslyfslpkekishiiftsnkqvkskedal
nnpyvkvmrrlgiidesqvifwdslkqlggglehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii6A (A:)
mktitlyldpaslpalnqlmdftqnnedkthprifglsrfkipdniitqyqnihfvelkd
nrptealftildqypgnielnihlniahsvqlirpilayrfkhldrvsiqqlnlydngsm
eyvdlekeenkdisaeikqaekqlshylltgkikfdnptiaryvwqsafpvkyhflstdy
fekaeflqplkeylaenyqkmdwtayqqltpeqqafyltlvgfndevkqslevqqakfif
tgtttwegntdvreyyaqqqlnllnhftqaegdlfigdhykiyfkghprggeindyilnn
aknitnipanisfevlmmtgllpdkvggvasslyfslpkekishiiftsnkqvkskedal
nnpyvkvmrrlgiidesqvifwdslkqlgggle