PDB entry 2ii4

View 2ii4 on RCSB PDB site
Description: Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Coenzyme A-bound form
Class: transferase
Keywords: cubic core, homo trimer, CoA-bound form, TRANSFERASE
Deposited on 2006-09-27, released 2006-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4a_
  • Chain 'B':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4b_
  • Chain 'C':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4c_
  • Chain 'D':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4d_
  • Chain 'E':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4e_
  • Chain 'F':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4f_
  • Chain 'G':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4g_
  • Chain 'H':
    Compound: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
    Species: Bos taurus [TaxId:9913]
    Gene: DBT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2ii4h_
  • Heterogens: CL, COA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2ii4A (A:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4A (A:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2ii4B (B:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4B (B:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2ii4C (C:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4C (C:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2ii4D (D:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4D (D:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ii4E (E:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4E (E:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ii4F (F:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4F (F:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2ii4G (G:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4G (G:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2ii4H (H:)
ghaeimppppkpkdrtipipiskppvfigkdrtepvkgfhkamvktmsaalkiphfgycd
evdltelvklreelkpiafargiklsfmpfflkaaslgllqfpilnasvdencqnityka
shnigiamdteqglivpnvknvqirsifeiatelnrlqklgsagqlstndliggtftlsn
igsiggtyakpvilppevaigalgtikalprfnekgevckaqimnvswsadhriidgatv
srfsnlwksylenpafmlldlk

    Sequence, based on observed residues (ATOM records): (download) 
    >2ii4H (H:)
gkdrtepvkgfhkamvktmsaalkiphfgycdevdltelvklreelkpiafargiklsfm
pfflkaaslgllqfpilnasvdencqnitykashnigiamdteqglivpnvknvqirsif
eiatelnrlqklgsagqlstndliggtftlsnigsiggtyakpvilppevaigalgtika
lprfnekgevckaqimnvswsadhriidgatvsrfsnlwksylenpafmlldlk